1627-28-7 Usage
General Description
6-Chlorothymine is a synthetic chemical compound with the molecular formula C5H6ClN2O2. It is a derivative of thymine, one of the four nucleobases found in DNA. 6-Chlorothymine is used in the study of nucleic acids and nucleotides, particularly in the investigation of DNA replication and repair mechanisms. It has been shown to inhibit the growth of certain cancer cell lines, making it a potential candidate for anticancer drug development. Additionally, 6-Chlorothymine has been used in research to investigate the effects of DNA modifications on gene expression and epigenetics. It is important for its role in understanding the structure and function of DNA and its potential applications in medical research.
Check Digit Verification of cas no
The CAS Registry Mumber 1627-28-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,2 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1627-28:
(6*1)+(5*6)+(4*2)+(3*7)+(2*2)+(1*8)=77
77 % 10 = 7
So 1627-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2O2/c1-2-3(6)7-5(10)8-4(2)9/h1H3,(H2,7,8,9,10)
1627-28-7Relevant articles and documents
IMAGING AGENTS
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Page/Page column 18, (2019/06/17)
The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.
Functionalization of unprotected uracil derivatives using the halogen - Magnesium exchange
Kopp, Felix,Knoechel, Paul
, p. 1639 - 1641 (2008/02/02)
The reaction of commercially available 5-iodouracil with 2 equiv of MeMgCl in the presence of LiCl, followed by the addition of i-PrMgCl-LiCl, provides the corresponding trimagnesiated species, which reacts with various electrophiles to give selectively 5
