16275-33-5Relevant articles and documents
Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase
Van Linden, Oscar P.J.,Farenc, Carine,Zoutman, Willem H.,Hameetman, Liesbeth,Wijtmans, Maikel,Leurs, Rob,Tensen, Cornelis P.,Siegal, Gregg,De Esch, Iwan J.P.
supporting information; experimental part, p. 493 - 500 (2012/03/11)
The in silico identification, optimization and crystallographic characterization of a 6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine scaffold as an inhibitor for the EPHA4 receptor tyrosine kinase is described. A database containing commercially