1627503-04-1Relevant articles and documents
Metal-free oxidative cyclization of o-acylphenols for the construction of 2-aminobenzofuran-3(2H)-ones
Yu, Hui,Huang, Weihua,Zhang, Fengling
, p. 3156 - 3162 (2014)
An efficient metal-free approach to the synthesis of 2-aminobenzofuran- 3(2H)-ones has been developed. Using TBHP as an oxidant and I2 (or TBAI) as catalyst, 2-acylphenols were treated with secondary amines to provide 2-aminobenzofuran-3(2H)-one derivatives in moderate to good yields. A possible reaction pathway for the formation of 2-dimorpholinobenzofuran-3(2H)-one is also discussed herein. Copyright