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1627749-02-3

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1627749-02-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1627749-02-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,7,7,4 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1627749-02:
(9*1)+(8*6)+(7*2)+(6*7)+(5*7)+(4*4)+(3*9)+(2*0)+(1*2)=193
193 % 10 = 3
So 1627749-02-3 is a valid CAS Registry Number.

1627749-02-3Downstream Products

1627749-02-3Relevant articles and documents

Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists

Rudolph, Dale A.,Alcazar, Jesus,Ameriks, Michael K.,Anton, Ana Belen,Ao, Hong,Bonaventure, Pascal,Carruthers, Nicholas I.,Chrovian, Christa C.,De Angelis, Meri,Lord, Brian,Rech, Jason C.,Wang, Qi,Bhattacharya, Anindya,Andres, Jose Ignacio,Letavic, Michael A.

, p. 3157 - 3163 (2015)

Abstract The optimization efforts that led to a novel series of methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones that are potent rat and human P2X7 antagonists are described. These efforts resulted in the discovery of co

N - acyl - [...] P 2X7 adjustment

-

, (2017/10/28)

The present invention is directed to compounds of Formula (I), which includes enantiomer and diasteromers thereof: These compounds are suitable for use in the treatment of diseases associated with P2X7 receptor activity such as diseases of the autoimmune

P2X7 MODULATORS

-

Paragraph 0126; 0360, (2014/09/30)

The present invention is directed to a compound of Formula (I) and to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.

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