16282-49-8

Basic information

• Product Name: Oxirane, 2-cyclopropyl-2-phenyl-
• CAS NO: 16282-49-8
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 16282-49-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxirane, 2-cyclopropyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxirane, 2-cyclopropyl-2-phenyl-(16282-49-8)
• EPA Substance Registry System: Oxirane, 2-cyclopropyl-2-phenyl-(16282-49-8)

Safety Data

• Hazardous Substances Data: 16282-49-8(Hazardous Substances Data)

Upstream product

• 825-76-3 α-cyclopropylstyrene 

Downstream Products

• 58368-44-8 5-Methoxy-2-phenylpent-2-en-1-ol 
• 58368-42-6 1-Cyclopropyl-1-phenyl-ethan-1,2-diol 
• 16282-50-1 2-cyclopropyl-2-phenylacetaldehyde 

Relevant articles and documents

Aldehyde-catalyzed epoxidation of unactivated alkenes with aqueous hydrogen peroxide

The organocatalytic epoxidation of unactivated alkenes using aqueous hydrogen peroxide provides various indispensable products and intermediates in a sustainable manner. While formyl functionalities typically undergo irreversible oxidations when activating an oxidant, an atropisomeric two-axis aldehyde capable of catalytic turnover was identified for high-yielding epoxidations of cyclic and acyclic alkenes. The relative configuration of the stereogenic axes of the catalyst and the resulting proximity of the aldehyde and backbone residues resulted in high catalytic efficiencies. Mechanistic studies support a non-radical alkene oxidation by an aldehyde-derived dioxirane intermediate generated from hydrogen peroxide through the Payne and Criegee intermediates.