162930-57-6

Basic information

• Product Name: 2-amino-3-nitro-N-propylbenzamide
• Synonyms: 2-amino-3-nitro-N-propylbenzamide
• CAS NO: 162930-57-6
• Molecular Weight: 223.232
• Mol File: 162930-57-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-amino-3-nitro-N-propylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-3-nitro-N-propylbenzamide(162930-57-6)
• EPA Substance Registry System: 2-amino-3-nitro-N-propylbenzamide(162930-57-6)

Safety Data

• Hazardous Substances Data: 162930-57-6(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 606-18-8 3-nitroanthranilic acid 

Downstream Products

• 1025824-91-2 3-Propylaminomethyl-benzene-1,2-diamine 

Relevant articles and documents

Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1,3-benzoazole derivatives bearing amide units

A series of 1,3-benzoazole derivatives possessing amide moieties were designed, synthesized and evaluated as inhibitors against human dihydroorotate dehydrogenase (hDHODH). Compounds A11, A14 and A26 exhibited good to excellent activities against hDHODH at the concentration of 10 μM. In particular, compound A14 displayed an IC50 value of 0.178 μM with 2-fold preference over A771726. The result implied that a proper degree of steric size and electron density of the C-6 amide moiety was necessary to retain the inhibitory activity of the synthesized compounds.