1629670-53-6Relevant articles and documents
Azo-sulforhodamine dyes: A novel class of broad spectrum dark quenchers
Chevalier, Arnaud,Renard, Pierre-Yves,Romieu, Anthony
, p. 3946 - 3949 (2014)
A rapid access to a novel class of water-soluble dark quencher dyes was achieved using an azo-coupling reaction between a fluorescent primary arylamine derived from a sulforhodamine 101 scaffold and a tertiary aniline equipped with different bioconjugatable groups. The thus obtained nonfluorescent azo-sulforhodamine hybrids display a broad quenching range spanning the visible to NIR regions. This was demonstrated through the preparation and enzymatic activation of FRET-based fluorogenic substrates of urokinase.