1630043-93-4

Basic information

• Product Name: (2-chloropyridin-3-yl)(2-isothiocyanatophenyl)methanone
• Synonyms: (2-chloropyridin-3-yl)(2-isothiocyanatophenyl)methanone
• CAS NO: 1630043-93-4
• Molecular Weight: 274.73
• Mol File: 1630043-93-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-chloropyridin-3-yl)(2-isothiocyanatophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloropyridin-3-yl)(2-isothiocyanatophenyl)methanone(1630043-93-4)
• EPA Substance Registry System: (2-chloropyridin-3-yl)(2-isothiocyanatophenyl)methanone(1630043-93-4)

Safety Data

• Hazardous Substances Data: 1630043-93-4(Hazardous Substances Data)

Upstream product

• 1630043-87-6 N-{2-[(2-chloropyridin-3-yl)(hydroxy)methyl]phenyl}formamide 
• 25559-38-0 N-formyl-2-aminobenzaldehyde 
• 1630043-90-1 N-{2-[(2-chloropyridin-3-yl)carbonyl]phenyl}formamide 
• 109-09-1 2-chloropyridine 

Relevant articles and documents

Synthesis of N,N-dialkyl-5(or 10)-oxobenzo[B][1,8 or 1,7(or 1,6)]naphthyridine-10(5H)(or 5(10H))-carbothioamides based on the reaction of the respective (chloropyridinyl)(2-isothiocyanatophenyl)methanones with secondary amines

The addition of secondary amines to (2-chloropyridin-3-yl)(2- isothiocyanatophenyl)methanone, derived from 2-chloropyridine and N-(2- formylphenyl)formamide, followed by treatment of the resulting thiourea intermediates with sodium hydride has proven to provide a method for the synthesis of N,N-dialkyl-5-oxobenzo[b][1,8]naphthyridine-10(5H)- carbothioamides. Similarly, N,N-dialkyl-5-oxobenzo[b][1,7]naphthyridine- 10(5H)-carbothioamides and N,N-dialkyl-10-oxobenzo[b][1,6]naphthyridine- 5(10H)-carbothioamides can be prepared from the respective (chloropyridinyl)(2- isothiocyanatophenyl)methanones.