1630808-89-7 Usage
General Description
The chemical "1-[(4-{[4-(6-fluoro-1,3-benzoxazol-2-yl)phenyl]carbonyl}piperazin-1-yl)carbonyl]cyclopropan-1-ol" is a complex compound with several functional groups. It contains a cyclopropane ring and a piperazine ring connected to a benzoxazole moiety, as well as a carbonyl group. 1-[(4-{[4-(6-fluoro-1,3-benzoxazol-2-yl)phenyl]carbonyl}piperazin-1-yl)carbonyl]cyclopropan-1-ol is likely to have a variety of pharmacological properties due to the presence of these functional groups, and could potentially be used in the development of new drugs for a range of medical conditions. However, further research and testing would be necessary to determine its specific potential uses and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 1630808-89-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,0,8,0 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1630808-89:
(9*1)+(8*6)+(7*3)+(6*0)+(5*8)+(4*0)+(3*8)+(2*8)+(1*9)=167
167 % 10 = 7
So 1630808-89-7 is a valid CAS Registry Number.
1630808-89-7Relevant articles and documents
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN)
Martin, Matthew W.,Lancia, David R.,Li, Hongbin,Schiller, Shawn E.R.,Toms, Angela V.,Wang, Zhongguo,Bair, Kenneth W.,Castro, Jennifer,Fessler, Shawn,Gotur, Deepali,Hubbs, Stephen E.,Kauffman, Goss S.,Kershaw, Mark,Luke, George P.,McKinnon, Crystal,Yao, Lili,Lu, Wei,Millan, David S.
, p. 1001 - 1006 (2019)
The discovery, structure-activity relationships, and optimization of a novel class of fatty acid synthase (FASN) inhibitors is reported. High throughput screening identified a series of substituted piperazines with structural features that enable interactions with many of the potency-driving regions of the FASN KR domain binding site. Derived from this series was FT113, a compound with potent biochemical and cellular activity, which translated into excellent activity in in vivo models.
