1632352-36-3

Basic information

• Product Name: (S)-6-bromo-4'-methoxy-2'-methyl-1,2,3,4-tetrahydro-1,1'-biphenyl
• Synonyms: (S)-6-bromo-4'-methoxy-2'-methyl-1,2,3,4-tetrahydro-1,1'-biphenyl
• CAS NO: 1632352-36-3
• Molecular Weight: 281.192
• Mol File: 1632352-36-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-6-bromo-4'-methoxy-2'-methyl-1,2,3,4-tetrahydro-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-6-bromo-4'-methoxy-2'-methyl-1,2,3,4-tetrahydro-1,1'-biphenyl(1632352-36-3)
• EPA Substance Registry System: (S)-6-bromo-4'-methoxy-2'-methyl-1,2,3,4-tetrahydro-1,1'-biphenyl(1632352-36-3)

Safety Data

• Hazardous Substances Data: 1632352-36-3(Hazardous Substances Data)

Upstream product

• 148706-30-3 2-methyl-4-methoxyphenylmagnesium bromide 
• 50870-61-6 2-bromocyclohex-2-en-1-one 
• 61426-49-1 (1R)-2-bromocyclohex-2-en-1-ol 
• 930-68-7 cyclohexenone 

Downstream Products

• 1632352-37-4 (S)-methyl 6-hydroxy-2-(4-methoxy-2-methylphenyl)hexanoate 
• 1632352-38-5 (S)-6-((tert-butyldiphenylsilyl)oxy)-2-(4-methoxy-2-methylphenyl)hexan-1-ol 
• 1632352-39-6 (S)-6-((tert-butyldiphenylsilyl)oxy)-2-(4-methoxy-2-methylphenyl)hexyl methanesulfonate 
• 1632352-40-9 (S)-5-(4-methoxy-2-methylphenyl)hexan-1-ol 

Relevant articles and documents

Allylic substitution of esters derived from 2-bromocyclohex-2-enol with aryl copper reagents and synthetic utilization of the derived anti s N2′ products

Allylic substitution of esters derived from 2-bromocyclohex-2-enol with PhMgBr-based copper reagent was investigated to find high anti S N2′ selectivity with the diethyl phosphate, whereas other esters such as picolinate, acetate, and mesylate resulted in partial racemization or recovery of the starting esters. This protocol was applied to the copper reagent derived from 2-Me-4-MeOC6H3MgBr and CuBr·SMe2 and the olefin part of the anti S N2′ product was cleaved for a synthesis of patchouli alcohol. Georg Thieme Verlag Stuttgart New York.