16335-43-6Relevant articles and documents
Crandall et al.
, p. 2911 (1972)
Another Role of Copper in the SimmonsSmith Reaction: Copper-catalyzed Nucleophilic Michael-type Cyclopropanation of a,β-Unsaturated Ketones
Fujii, Kanami,Misaki, Tomonori,Sugimura, Takashi
, p. 634 - 636 (2014/05/20)
Cyclopropanation was performed using the Furukawa procedure with CH2I2/Et2Zn and a,β-unsaturated ketones. The reaction was performed in the presence of a copper salt. The reactivity was highly dependent on the substrate structure, and cyclopropanated products were obtained in better yields than those achieved using the original SimmonsSmith conditions with a ZnCu couple in some cases. Stereospecificity was observed in a certain case; however, the synthesis of an asymmetric version with a chiral ligand was not successful.
The Chromium Trioxide-3,5-Dimethylpyrazole Complex: a Mild and Selective Reagent for the Oxidation of Cyclopropyl Hydrocarbons
Banwell, Martin G.,Haddad, Najiba,Huglin, Julie A.,MacKay, Maureen F.,Reum, Monica E.,et al.
, p. 954 - 957 (2007/10/02)
The title complex selectively oxidises the methylene unit adjacent to a cyclopropane ring producing synthetically useful yields of the corresponding cyclopropyl ketones and/or products resulting from cleavage of the three-membered ring.