163458-23-9

Basic information

• Product Name: Methyl (+/-)-2-hydroxy-3-(2-methyl-1,3-dioxolan-2-yl)propanoate
• Synonyms: Methyl (+/-)-2-hydroxy-3-(2-methyl-1,3-dioxolan-2-yl)propanoate
• CAS NO: 163458-23-9
• Molecular Weight: 190.196
• Mol File: 163458-23-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl (+/-)-2-hydroxy-3-(2-methyl-1,3-dioxolan-2-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (+/-)-2-hydroxy-3-(2-methyl-1,3-dioxolan-2-yl)propanoate(163458-23-9)
• EPA Substance Registry System: Methyl (+/-)-2-hydroxy-3-(2-methyl-1,3-dioxolan-2-yl)propanoate(163458-23-9)

Safety Data

• Hazardous Substances Data: 163458-23-9(Hazardous Substances Data)

Upstream product

• 35351-33-8 methyl 3‐(2‐methyl‐1,3‐dioxolan‐2‐yl)propanoate 
• 137623-64-4 Davis' oxaziridine 

Relevant articles and documents

Synthesis of (+)- and (-)-N-BOC-7-azabicyclo[2.2.1]heptan-2-ones, versatile intermediates for the enantiospecific synthesis of (+)- and (-)-epibatidine and analogues

(+)- and (-)-Epibatidine, nonopiate antinociceptive alkaloids, have been prepared from (-)- and (+)-N-BOC-7-azabicyclo[2.2.1]heptan-2-one which were produced by resolution of the racemic mixture of the corresponding alcohols obtained in the previous racemic synthesis. In the present work, we report the enantiospecific synthesis of (-)- and (+)-N-BOC-7-azabicyclo[2.2.1]heptan-2-one from L-glutamic acid and levulinic acid. Also, this report describes the selective formation of trans-2,3-disubstituted-7-azabicyclo[2.2.1]heptanes from N-benzyl-5-(1'-methoxycarbonyl-3'-exobutyl)proline via a decarbonylation/iminium ion cyclization process. These functionalized intermediates are of potential value for the enantiospecific synthesis of epibatidine analogues.