163617-85-4Relevant articles and documents
Synthesis and structure-activity relationship of new 1,5-dialkyl-1,5- benzodiazepines as cholecystokinin-2 receptor antagonists
Roberts, Karen,Ursini, Antonella,Barnaby, Robert,Cassar, Paolo G.,Corsi, Mauro,Curotto, Giovanni,Donati, Daniele,Feriani, Aldo,Finizia, Gabriella,Marchioro, Carla,Niccolai, Daniela,Oliosi, Beatrice,Polinelli, Stefano,Ratti, Emiliangelo,Reggiani, Angelo,Tedesco, Giovanna,Tranquillini, Maria E.,Trist, David G.,Van Amsterdam, Franciscus T.M.
experimental part, p. 4257 - 4273 (2011/08/21)
This article deals with the synthesis and the activities of some 1,5-dialkyl-3-arylureido-1,5-benzodiazepin-2,4-diones which were prepared as potential CCK2 antagonists, with the intention to find a possible follow up of our lead compound GV150013, showin