16383-57-6Relevant articles and documents
β-Stereoselective phosphorylations applied to the synthesis of ADP- and polyprenyl-β-mannopyranosides
Li, Tianlei,Tikad, Abdellatif,Pan, Weidong,Vincent, Stphane P.
, p. 5628 - 5631 (2014)
An efficient and convenient synthetic route to glycosyl 1-β-phosphates has been developed using diallyl chlorophosphate as a phosphorylating agent with 4-N,N-dimethylaminopyridine under mild conditions. Diallyl-glycosyl 1-β-phosphate triesters of d-manno, l-glycero-d-manno-hepto-, d-gluco-, d-galacto-, and l-fuco-pyranose as well as lactose have been obtained by this strategy in good yields and excellent β-selectivities. Furthermore, the diallyl 6-azido-mannosyl 1-β-phosphate 2 was deprotected under mild conditions and converted into potentially clickable analogues of β-mannosyl phosphoisoprenoids I and ADP-heptose II.
PHOSPHOLIPID ETHER CONJUGATES AS CANCER-TARGETING DRUG VEHICLES
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Paragraph 000163, (2021/03/19)
Disclosed herein are therapeutic compounds capable of targeting a broad range of tumor cells. The present disclosure is further directed to compositions comprising the therapeutic compounds, methods of manufacturing the therapeutic compounds, and methods of treating cancer comprising administering the therapeutic compounds.
Curcumin phosphate compound, preparation method and uses thereof
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Paragraph 0096; 0097; 0098, (2016/10/08)
The present invention relates to a curcumin phosphate compound, a preparation method and uses thereof, and belongs to the field of pharmaceutical chemistry, wherein the structural general formula of the compound is defined in the specification, X is O or