1638642-77-9

Basic information

• Product Name: 2-methoxy-8-methyl-3-(4-nitrophenyl)-4-phenylisoquinolin-1(2H)-one
• Synonyms: 2-methoxy-8-methyl-3-(4-nitrophenyl)-4-phenylisoquinolin-1(2H)-one
• CAS NO: 1638642-77-9
• Molecular Weight: 386.407
• Mol File: 1638642-77-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methoxy-8-methyl-3-(4-nitrophenyl)-4-phenylisoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-8-methyl-3-(4-nitrophenyl)-4-phenylisoquinolin-1(2H)-one(1638642-77-9)
• EPA Substance Registry System: 2-methoxy-8-methyl-3-(4-nitrophenyl)-4-phenylisoquinolin-1(2H)-one(1638642-77-9)

Safety Data

• Hazardous Substances Data: 1638642-77-9(Hazardous Substances Data)

Upstream product

• 1942-30-9 4-(phenylethynyl)nitrobenzene 
• 57139-25-0 N-methoxy-2-methylbenzamide 

Relevant articles and documents

Organocatalytic oxidative annulation of benzamide derivatives with alkynes

Organocatalytic annulation by functionalization of benzamide derivatives with alkynes has been developed. We report a new approach of cycloaddition under mild reaction conditions using simple catalysts, such as iodobenzene and peracetic acid, as oxidant. Those novel, mild reaction conditions provided a straightforward synthesis of isoquinolones with fast reaction rate. Notable selectivity in annulation of unsymmetrically disubstituted alkynes was demonstrated.