1639207-42-3

Basic information

• Product Name: 2-MCPD 1,3-dioleate
• CAS NO: 1639207-42-3
• Molecular Weight: 639.443
• Mol File: 1639207-42-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-MCPD 1,3-dioleate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MCPD 1,3-dioleate(1639207-42-3)
• EPA Substance Registry System: 2-MCPD 1,3-dioleate(1639207-42-3)

Safety Data

• Hazardous Substances Data: 1639207-42-3(Hazardous Substances Data)

Upstream product

• 112-80-1 cis-Octadecenoic acid 
• 497-04-1 2-chloro-propane-1,3-diol 

Relevant articles and documents

Synthesis of 2-Monochloropanol Fatty Acid Esters and Their Acute Oral Toxicities in Swiss Mice

A novel synthetic route was designed, developed, and utilized to synthesize six high-purity 2-monochloropropanediol fatty acid esters (2-MCPD esters), a group of potential processing-induced food contaminants. A chlorine atom was introduced to C-2 of a diethyl malonate molecule, which was reduced by NaBH4 and followed by esterification using fatty acids. The reaction products were isolated and purified using silica gel columns to obtain three 2-MCPD monoesters and three diesters at about 50-54% and 56-59% yields, respectively. In addition, 2-MCPD monopalmitate and dipalmitate were examined for their acute oral toxicities in Swiss mice. The LD50 values of 2-MCPD mono- and dipalmitate were greater than 5000 mg/kg body weight (BW), along with detectable nephrotoxicity and testicular toxicity. The results of this study may promote future investigation of MCPD ester toxicology and detection.