163930-30-1

Basic information

• Product Name: 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE
• Synonyms: 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE
• CAS NO: 163930-30-1
• Molecular Formula: C₁₅H₁₅IO
• Molecular Weight: 338.18
• Mol File: 163930-30-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 398.0±30.0 °C(Predicted)
• Appearance: /
• Density: 1.497±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE(163930-30-1)
• EPA Substance Registry System: 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE(163930-30-1)

Safety Data

• Hazardous Substances Data: 163930-30-1(Hazardous Substances Data)

Usage

Description

1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE is a chemical compound with the molecular formula C15H17IO. It is a benzene derivative featuring a phenoxy group and an iodoethyl group attached to the benzene ring. 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE is commonly utilized in research and manufacturing, with its specific applications depending on the context in which it is used.

Uses

1. Used in Organic Synthesis:
1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE is used as an intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
2. Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE is used as a starting material or a key intermediate in the development of new drugs. Its structural features can be exploited to design and synthesize novel bioactive molecules with potential therapeutic applications.
3. Used in Chemical Research:
1-((4-(2-IODOETHYL)PHENOXY)METHYL)BENZENE is also employed in chemical research to study various reaction mechanisms, explore new synthetic routes, and develop innovative methodologies in organic chemistry. Its unique properties and reactivity can provide insights into the behavior of similar compounds and contribute to the advancement of chemical science.

Upstream product

• 61439-59-6 2-(4-benzyloxyphenyl)ethanol 
• 61439-60-9 1-benzyloxy-4-(2-methanesulfonyloxyethyl)benzene 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 36438-64-9 p-benzyloxystyrene 
• 123-08-0 4-hydroxy-benzaldehyde 
• 100-39-0 benzyl bromide 

Downstream Products

• 692754-92-0 {1-hydroxymethyl-1-[2-(4-hydroxy-phenyl)-ethyl]-but-3-ynyl}-carbamic acid tert-butyl ester 
• 634893-09-7 (S)-2-Amino-2-[2-(4-benzyloxy-phenyl)-ethyl]-pent-4-ynoic acid ethyl ester 
• 692754-99-7 {4-hydroxy-1-hydroxymethyl-1-[2-(4-hydroxy-phenyl)-ethyl]-butyl}-carbamic acid tert-butyl ester 
• 634893-10-0 (S)-2-Amino-2-[2-(4-benzyloxy-phenyl)-ethyl]-5-hydroxy-pentanoic acid ethyl ester 
• 634893-13-3 {1-[2-(4-benzyloxy-phenyl)-ethyl]-1-hydroxymethyl-but-3-ynyl}-carbamic acid tert-butyl ester 
• 634893-14-4 {1-[2-(4-benzyloxy-phenyl)-ethyl]-4-hydroxy-1-hydroxymethyl-butyl}-carbamic acid tert-butyl ester 
• 634893-05-3 (2S,5R)-2-[2-(4-Benzyloxy-phenyl)-ethyl]-3,6-diethoxy-5-isopropyl-2-prop-2-ynyl-2,5-dihydro-pyrazine 
• 634893-17-7 {1-[2-(4-heptyloxy-phenyl)-ethyl]-1-hydroxymethyl-but-3-ynyl}-carbamic acid tert-butyl ester 
• 634893-06-4 3-{(2S,5R)-2-[2-(4-Benzyloxy-phenyl)-ethyl]-3,6-diethoxy-5-isopropyl-2,5-dihydro-pyrazin-2-yl}-propan-1-ol 
• 634893-18-8 {1-[2-(4-heptyloxy-phenyl)-ethyl]-4-hydroxy-1-hydroxymethyl-butyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

One-Pot Deoxygenation and Substitution of Alcohols Mediated by Sulfuryl Fluoride

Sulfuryl fluoride is a valuable reagent for the one-pot activation and derivatization of aliphatic alcohols, but the highly reactive alkyl fluorosulfate intermediates limit both the types of reactions that can be accessed as well as the scope. Herein, we report the SO2F2-mediated alcohol substitution and deoxygenation method that relies on the conversion of fluorosulfates to alkyl halide intermediates. This strategy allows the expansion of SO2F2-mediated one-pot processes to include radical reactions, where the alkyl halides can also be exploited in the one-pot deoxygenation of primary alcohols under mild conditions (52-95% yield). This strategy can also enhance the scope of substitutions to nucleophiles that are previously incompatible with one-pot SO2F2-mediated alcohol activation and enables substitution of primary and secondary alcohols in 54-95% yield. Chiral secondary alcohols undergo a highly stereospecific (90-98% ee) double nucleophilic displacement with an overall retention of configuration.

C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS

The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.

DIARYL ETHER DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT

The present invention provides diaryl ether derivatives that exhibit significant immunosuppressive effects with less side effects. The diaryl derivatives of the present invention are represented by the following general formula (1): ???one example is 2-amino-2-[4-(3-benzyloxyphenoxy)-2-chlorophenyl)propyl-1,3-propanediol.