163979-81-5

Basic information

• Product Name: 2-(1-Ethylsulfanyl-2-methyl-propyl)-cyclohexanone
• Synonyms: 2-(1-Ethylsulfanyl-2-methyl-propyl)-cyclohexanone
• CAS NO: 163979-81-5
• Molecular Weight: 214.372
• Mol File: 163979-81-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(1-Ethylsulfanyl-2-methyl-propyl)-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Ethylsulfanyl-2-methyl-propyl)-cyclohexanone(163979-81-5)
• EPA Substance Registry System: 2-(1-Ethylsulfanyl-2-methyl-propyl)-cyclohexanone(163979-81-5)

Safety Data

• Hazardous Substances Data: 163979-81-5(Hazardous Substances Data)

Upstream product

• 7334-57-8 1,1-di(ethylthio)-2-methylpropane 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 163979-78-0 Acetic acid 1-ethylsulfanyl-2-methyl-propyl ester 
• 108-94-1 cyclohexanone 
• 78-84-2 isobutyraldehyde 
• 75-08-1 ethanethiol 

Relevant articles and documents

Thiol-promoted selective addition of ketones to aldehydes

A simple and efficient thiol-mediated addition of ketones to aromatic and aliphatic aldehydes is reported. This thermodynamically controlled Pummerer/aldol reaction, which can tolerate both moisture and protic functional groups, provides a direct entry to syn-β-thioketones in high chemo- and regioselectivity. Mechanistic studies revealed that selective transformation of the aldehyde to an electrophilic thionium ion species concurrent with the generation of a nucleophilic vinyl sulfide coupling partner from the ketone is imposing cross-coupling over dimerization.

A CONVENIENT METHOD FOR THE PREPARATION OF γ-KETOSULFIDES FROM THIOACETALS

In the presence of trityl tetrafluoroborate, silyl enol ethers react with thioacetals to give the corresponding γ-ketosulfides in good yields with high stereoselectivity.In a similar manner, γ-ketosulfides are obtained in good yields by the one pot reacti