16401-14-2 Usage
Description
5-FORMYLISOXAZOLE is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its isoxazole ring structure with a formyl group attached, which contributes to its reactivity and utility in chemical reactions.
Uses
Used in Pharmaceutical Synthesis:
5-FORMYLISOXAZOLE is used as a reagent for the synthesis of N-(benzo[1,2,3]triazol-1-yl)-N-((benzyl)acetamido)phenyl carboxamides, which are known as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors. These inhibitors play a crucial role in the development of antiviral drugs targeting SARS-CoV and related coronaviruses.
5-FORMYLISOXAZOLE is also used as a reagent in the synthesis of TC-6683, an α4β2 nicotinic acetylcholine receptor agonist. 5-FORMYLISOXAZOLE is being investigated for its potential in treating cognitive disorders, such as Alzheimer's disease and other forms of dementia, by modulating the neurotransmission in the brain.
Check Digit Verification of cas no
The CAS Registry Mumber 16401-14-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,4,0 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16401-14:
(7*1)+(6*6)+(5*4)+(4*0)+(3*1)+(2*1)+(1*4)=72
72 % 10 = 2
So 16401-14-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H3NO2/c6-3-4-1-2-5-7-4/h1-3H
16401-14-2Relevant articles and documents
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Adembri,G. et al.
, p. 4697 - 4707 (1967)
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INTEGRASE INHIBITORS 3
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Page/Page column 61, (2008/06/13)
The present invention provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Compounds of formula (I) are also provided.
