16439-95-5Relevant articles and documents
Analgesic and antioxidant activities of 4-phenyl-1,5-benzodiazepin-2-one and its long carbon chains derivatives
Ongone, Terence Nguema,Achour, Redouane,El Ghoul, Mostafa,El Ouasif, Latyfa,El Jemli, Meryem,Chemlal, Laila,Cherrah, Yahia,Alaoui, Katim,Zellou, Amina
, (2019)
The aim of this work is to deepen the pharmacological effect of 4-phenyl-1,5-benzodiazepin-2-one derivatives which have a similar structure to nonionic surfactants: 4-phenyl-1,5-benzodiazepin-2-one is the hydrophilic head, and the carbon chain is hydropho
Hetaryl-1,5 Benzodiazepines—Part I: Synthesis of 3-pyrimidinyl- and Imidazolyl-1,5-benzodiazepines
Khodairy, Ahmed,Ahmed, Eman A.,Abdel Ghany, Hossam
, p. 242 - 247 (2017/02/03)
Nucleophilic substitution of 3-bromo-4-phenyl-1H-[1,5]benzodiazepin-2-one (1) with thiourea or guanidine in presence of potassium carbonate afforded 1,5-benzodiazepin-3-ylimidothiocarbamate 2 or 1,5-benzodiazepin-3-ylguanidine 3, respectively. Pyrimidylthiobenzodiazepines 5, 6, 7, 8, 9, 10, 11, 12, 13 were obtained via the reaction of compound 2 with malononitrile dimer, diethyl malonate, methylenemalononitriles, or a mixture of an aldehyde and β-keto esters or acetylacetone, catalyzed using ceric ammonium nitrate. Reaction of compound 2 or 3 with α-halo esters, nitriles, and/or ketones afforded imidazoles 14, 15, 16, 17, 18, 19, 20, respectively.
1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials
Mtiraoui, Hasan,Gharbi, Rafik,Msaddek, Moncef,Bretonnière, Yann,Andraud, Chantal,Sabot, Cyrille,Renard, Pierre-Yves
, p. 4720 - 4727 (2016/07/06)
Photoluminescent materials, that are now ubiquitous in our everyday life, have particularly attracted the attention of the scientific community these past few years due to potential important applications such as in bioimaging, sensing, or optoelectronics