164390-30-1 Usage
General Description
Ethyl 4-chloro-2-methylnicotinate is a chemical compound with the molecular formula C11H12ClNO2. It is a derivative of nicotinic acid and is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various compounds. ethyl 4-chloro-2-Methylnicotinate is often used as a building block for the production of pharmaceutical drugs, agricultural products, and other organic chemicals. It is known for its role as an important reactant in the synthesis of new compounds and as a precursor to various biologically active molecules.ethyl 4-chloro-2-Methylnicotinate is a yellow colored liquid with a melting point of 10-14°C and a boiling point of 248-250°C.
Check Digit Verification of cas no
The CAS Registry Mumber 164390-30-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,4,3,9 and 0 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 164390-30:
(8*1)+(7*6)+(6*4)+(5*3)+(4*9)+(3*0)+(2*3)+(1*0)=131
131 % 10 = 1
So 164390-30-1 is a valid CAS Registry Number.
164390-30-1Relevant articles and documents
One-Pot Synthesis of Highly Substituted Nicotinic Acid Derivatives Based on a Formylation Strategy of Enamino Keto Esters
Kumar, Sukeerthi,Sawant, Aarti A.,Chikhale, Rajendra P.,Karanjai, Keya,Thomas, Abraham
, p. 1645 - 1653 (2016/03/01)
(Chemical Equation Presented). A facile one-pot synthesis of 4-chloro or 4-bromonicotinic acid esters with optional 2- and 2,5-disubstitution on the pyridine ring has been developed from easily accessible enamino keto esters by a formylation followed by in situ intramolecular cyclization strategy under optimized Vilsmeier reaction conditions. The effect of the substituents on the β-carbon and the nature of the keto functionality were explored in detail to understand the mechanism of pyridine ring formation under the described conditions.
