164462-16-2Relevant articles and documents
PROCESS FOR MANUFACTURE OF A COMPLEXING AGENT
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Page/Page column 7; 8; 9, (2021/09/11)
A process for making a complexing agent with an enantiomeric excess of at least 60%, wherein said process comprises the following steps: (a) reacting an aqueous slurry of alanine with an enantiomeric excess of at least 60% with formaldehyde and hydrocyanic acid, thereby forming an aqueous solution of alanine- bisacetonitrile, (b) saponifying the alanine-bisacetonitrile from step (a) by combining the aqueous solution obtained in step (a) with an aqueous solution of alkali metal hydroxide.
Preparation method of dicarboxymethyl amino acid salt
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Paragraph 0032-0035, (2019/12/25)
The invention provides a preparation method of dicarboxylmethyl amino acid salt, and the method comprises the following steps: by using amino acids, liquid caustic soda and chloroacetic acid as raw materials, continuously synthesizing an N, N-dicarboxyl methyl amino acid salt solution product in a manner that materials are subjected to continuous two-stage liquid-liquid static mixing and then enter a continuous reactor for heating reaction. The method is beneficial to stabilization of product quality, high in product yield, capable of increasing the equipment utilization rate, shortening the production period and reducing the production cost, free of three wastes in the whole process, safe, environment-friendly and easy to realize large-scale production.
Preparation method of green chelating agent trisodium N,N-bis(carboxymethyl)alanine
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Paragraph 0014; 0017-0020, (2019/03/08)
The invention provides a preparation method of a green chelating agent trisodium N,N-bis(carboxymethyl)alanine. The method specifically comprises the steps as follows: partially or completely neutralized L-alanine and chloroacetic acid are subjected to an SN2 bimolecular nucleophilic substitution under an alkaline condition that the pH value is 10-12 in a water solution reaction system to producetrisodium methyl glutamate diacetate. In the reaction process, water in the reaction system is timely removed out at constant speed under the negative pressure of 0-minus 0.005 MPa, so that reaction substrates always keep higher reaction activity. The method is short in reaction cycle and simple in production process, and the production process is simple, and the product yield can reach 99%; chloroacetic acid replaces highly toxic substances such as hydrocyanic acid and the like, thus, the method is safe and environmentally friendly; produced water can be recycled to be used for reaction synthesis and product dilution, no toxic byproducts or wastewater is produced, the cost is low, and large-scale industrial production is facilitated.