164658-13-3 Usage
Description
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol, also known as CGP 60474, is a protein kinase C inhibitor that targets the CKD1/CDK2 enzymes. It is a complex organic compound with potential applications in the pharmaceutical industry, particularly in the development of cancer treatments.
Uses
Used in Pharmaceutical Industry:
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol is used as a protein kinase C inhibitor for the treatment of different cancers. It targets the CKD1/CDK2 enzymes, which play a crucial role in cell cycle regulation and are often dysregulated in cancer cells. By inhibiting these enzymes, CGP 60474 can potentially halt the growth and proliferation of cancer cells, making it a promising candidate for cancer therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 164658-13-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,4,6,5 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 164658-13:
(8*1)+(7*6)+(6*4)+(5*6)+(4*5)+(3*8)+(2*1)+(1*3)=153
153 % 10 = 3
So 164658-13-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24)
164658-13-3Relevant articles and documents
N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivatives
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Page 41, (2010/02/05)
The present invention relates to a method of protecting plants against attack or infestation by phytopathogenic organisms, such as nematodes or especially microorganisms, preferably fungi, bacteria and viruses, or combinations of two or more of these organisms, by applying at least one compound of the formula (I): wherein n is 0 or 1, R1 is halogen, alkoxy, haloalkyl, haloalkoxy or alkyl, R2 is hydrogen, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy, each of R3, R4 and R5 is, independently of the others, hydrogen, lower alkyl or halogen, and R6 is as defined in claim 1. The invention also relates to new compounds of formula (I), their preparation, use and compositions comprising said compound.
