16473-21-5

Basic information

• Product Name: Benzonitrile, 4-(fluoromethyl)-
• CAS NO: 16473-21-5
• Molecular Formula: C8H6FN
• Molecular Weight: 135.141
• Mol File: 16473-21-5.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-(fluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-(fluoromethyl)-(16473-21-5)
• EPA Substance Registry System: Benzonitrile, 4-(fluoromethyl)-(16473-21-5)

Safety Data

• Hazardous Substances Data: 16473-21-5(Hazardous Substances Data)

Upstream product

• 104-85-8 para-methylbenzonitrile 
• 455-18-5 4-CF₃C₆H₄CN 
• 3058-39-7 4-iodobenzonitrile 
• 874-89-5 4-Cyanobenzyl alcohol 
• 105-07-7 4-cyanobenzaldehyde 
• 87829-00-3 4-(hydrazonomethyl)benzonitrile 
• 373-52-4 bromofluoromethane 
• 126747-14-6 4-cyanophenylboronic acid 
• 373-53-5 fluoroiodomethane 
• 171364-82-2 4-cyanophenylboronic acid pinacol ester 
• 17201-43-3 4-cyanobenzyl bromide 
• 70135-28-3 (4-cyanophenyl)diazomethane 

Downstream Products

• 120427-54-5 4-(bromofluoromethyl)benzonitrile 
• 116450-83-0 4-(6-nitro-1-indolylmethyl)benzonitrile 
• 5462-71-5 4-cyanophenylacetic acid 
• 35505-99-8 (E) 3-(4-cyanophenyl)-1-phenyl-propene 
• 104-85-8 para-methylbenzonitrile 

Relevant articles and documents

The transmission of resonance effects through a methylene group-spectroscopic studies on some α-substituted-acetonitriles and p-toluonitriles

Frequencies and integrated intensities are recorded for the νCN mode of a representative selection of α-substituted acetonitriles, α-substituted-p-toluonitriles and β-substituted propionitriles.The frequencies of the acetonitriles are confirmed

PROCESSES FOR FLUORINATION

The present technology relates to fluorination reactions. Specifically, processes useful for making the fungicide compound, DFT are disclosed. More broadly, also disclosed herein are processes useful for deoxyfluorination at the α-aromatic position of a given compound.

Electrochemical-Promoted Nickel-Catalyzed Oxidative Fluoroalkylation of Aryl Iodides

This work describes a general strategy for metal-catalyzed cross-coupling of fluoroalkyl radicals with aryl halides under electrochemical conditions. The contradiction between anodic oxidation of fluoroalkyl sulfinates and cathodic reduction of low-valent nickel catalysts can be well addressed by paired electrolysis, allowing for direct introduction of fluorinated functionalities into aromatic systems.