164732-66-5

Basic information

• Product Name: 3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester
• Synonyms: 3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester
• CAS NO: 164732-66-5
• Molecular Weight: 203.241
• Mol File: 164732-66-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester(164732-66-5)
• EPA Substance Registry System: 3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester(164732-66-5)

Safety Data

• Hazardous Substances Data: 164732-66-5(Hazardous Substances Data)

Upstream product

• 7486-35-3 tri-n-butyl(vinyl)tin 
• 164732-59-6 6-Trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester 
• 1066-54-2 trimethylsilylacetylene 
• 203259-90-9 N-phenoxycarbonyl-1,2,5,6-tetrahydropyridine 
• 66893-76-3 2-methoxy-piperidine-1-carboxylic acid phenyl ester 
• 90838-83-8 1-phenoxycarbonyl-1,4-dihydropyridine 
• 675-20-7 piperidin-2-one 
• 164732-57-4 N-(phenyloxycarbonyl)piperidin-2-one 
• 1885-14-9 phenyl chloroformate 
• 16641-71-7 1-(phenoxycarbonyl)piperidine 

Downstream Products

• 203259-94-3 2-cyano-1,4,5,6-tetrahydro-1-pyridinecarboxylic acid phenyl ester 
• 1381963-84-3 phenyl 5-[3-benzyloxy-3-oxo-prop-1-enyl]-3,4-dihydro-2H-pyridine-1-carboxylate 
• 1421692-57-0 phenyl 2-(2,6-dimethoxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 1421692-65-0 phenyl 2-(2,6-diethoxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 1609582-63-9 phenyl 5-(2-ethoxy-1,1-difluoro-2-oxoethyl)-3,4-dihydro-2H-pyridine-1-carboxylate 

Relevant articles and documents

Substituted Dihydropyridine Synthesis by Dearomatization of Pyridines

Dearomatization is an effective method to transform readily available N-heterocycles into partially saturated motifs. Manipulation of dihydro-derivatives holds great potential and provides access to a variety of semi-saturated N-heterocyclic building blocks. However, current strategies are limited in scope and the use of sensitive reagents restricts the applicability in synthetic laboratories. Herein, we report the synthesis of a broad variety of N-substituted 1,4- and 1,2-dihydropyridines by very mild and selective reduction with amine borane for the first time.

Diastereoselective synthesis of 3-fluoro-2-substituted piperidines and pyrrolidines

A facile procedure for synthesis of trans-3-fluoro-2-substituted piperidines by utilizing electrophilic fluorination of cyclic enamines and Lewis acid mediated nucleophilic substitution has been developed. Also, optically active trans-2-allyl-3-fluorinate

Highly enantioselective introduction of bis(alkoxycarbonyl)methyl group into the 2-position of piperidine skeleton

Copper ion catalyzed carbon-carbon bond forming reaction of N-acyliminium ions with diaryl malonates was achieved with high enantioselectivity. The key intermediates in the method were 2-methoxy-3,4-didehydropiperidines, which were easily prepared through