1648-62-0

Basic information

• Product Name: (2beta,5alpha,17beta)-2-fluoro-3-oxoandrostan-17-yl acetate
• Synonyms: (2beta,5alpha,17beta)-17-(Acetyloxy)-2-fluoro-androstan-3-one
• CAS NO: 1648-62-0
• Molecular Formula: C₂₁H₃₁FO₃
• Molecular Weight: 350.4674
• Mol File: 1648-62-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 424°C at 760 mmHg
• Flash Point: 202.9°C
• Density: 1.13g/cm³
• Vapor Pressure: 2.13E-07mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: (2beta,5alpha,17beta)-2-fluoro-3-oxoandrostan-17-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2beta,5alpha,17beta)-2-fluoro-3-oxoandrostan-17-yl acetate(1648-62-0)
• EPA Substance Registry System: (2beta,5alpha,17beta)-2-fluoro-3-oxoandrostan-17-yl acetate(1648-62-0)

Safety Data

• Hazardous Substances Data: 1648-62-0(Hazardous Substances Data)

Usage

General Description

(2beta,5alpha,17beta)-2-fluoro-3-oxoandrostan-17-yl acetate is a synthetic androgen, or anabolic steroid, that is commonly used in the treatment of hormonal imbalances and certain medical conditions such as hypogonadism and delayed puberty. It is a derivative of testosterone and has similar effects on the body, including promoting muscle growth, increasing bone density, and enhancing physical performance. This chemical compound is often used as a performance-enhancing drug by athletes and bodybuilders due to its ability to improve muscle strength and endurance. However,

Upstream product

• 981-64-6 (5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate 
• 68522-43-0 3-Trimethylsiloxy-5α-androst-2-en-17β-ylacetat 
• 1868-96-8 17β-Acetoxy-2β-fluor-5α-androstan-3α-ol 
• 7199-33-9 3,17β-Diacetoxy-5β-androsten-(2) 

Downstream Products

• 1648-61-9 5α-androstan-2α-fluoro-3-one-17β-ol acetate 

Relevant articles and documents

Obtention d'α-fluorocetones par oxydation anodique de derives d'enol.

To obtain fluoroketones without the use of electrophilic fluorinating reagents, we have carried out the anodic oxidation of enol esters and enol ethers in acetonitrile/Et3N, 3HF solution.With enol esters the main product is a fluoroketone or an acetoxyketone respectively, depending on the structure of the starting compound.The enol ether cation-radicals seemed to be less reactive towards H2F3- ions than the corresponding enol ester ones.

α-FLUORINATION OF KETONES BY XENON AND IODOBENZENE DIFLUORIDES: A STEREOCHEMICAL EVIDENCE DEMONSTRATING THEIR MECHANISTIC DIFFERENCES

Xenon difluoride reacts smoothly with various steroid silyl enol ethers in the absence of any acid catalyst to afford stereoselectively α-oriented α-fluoroketones in good yields while iodotoluene difluoride reacts rather sluggishly with these silyl enol ethers to competitively produce β-oriented α-fluoro ketones, elimination and other nucleophilic substitution products.The observed stereochemical contrast clearly suggest an electrophilic and nucleophilic mechanism for these reactions, respectively.