16484-16-5

Basic information

• Product Name: 1H-Tetrazole, 5-iodo-1-phenyl-
• CAS NO: 16484-16-5
• Molecular Formula: C7H5IN4
• Molecular Weight: 272.048
• Mol File: 16484-16-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Tetrazole, 5-iodo-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole, 5-iodo-1-phenyl-(16484-16-5)
• EPA Substance Registry System: 1H-Tetrazole, 5-iodo-1-phenyl-(16484-16-5)

Safety Data

• Hazardous Substances Data: 16484-16-5(Hazardous Substances Data)

Upstream product

• 1197040-29-1 phenyl isocyanate 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 343945-95-9 5-acetyl-1-phenyl-1H-tetrazole 

Downstream Products

• 5097-82-5 5-phenyl-1H-tetrazolone 
• 5378-52-9 phenyl-1H-tetrazole 

Relevant articles and documents

Cytostatic tetrazole-butenolide conjugates: Linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances

A series of tetrazoles linked to the butenolide core via benzene rings were prepared by the Stille coupling reaction of α-(tributylstannyl) butenolides and 5-(alkylsulfanyl)-1-(4-iodophenyl)tetrazoles, and the compounds were tested for antifungal and cytostatic activity. Interesting antifungal activities against the filamentous strain Absidia corymbifera, and cytostatic activities against leukemic cells HL-60 and CCRF-CEM were found. The cytostatic activity requires the presence of both the butenolide ring and the alkylsulfanyl group bound to tetrazole ring. In addition, the feasibility of Pd-coupling reactions with 5-iodotetrazoles was evaluated.

5-Halo-1-phenyltetrazoles

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