16489-90-0

Basic information

• Product Name: 6-ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline
• Synonyms: 6-ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline;1,2,3,4-Tetrahydro-2,2,4-trimethyl-6-ethoxyquinoline;2,2,4-Trimethyl-6-ethoxy-1,2,3,4-tetrahydroquinoline;6-Ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline,97%;Einecs 240-546-9;6-ethoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline hydrobromide;6-ethoxy-2,2,4-trimethyl-3,4-dihydro-1H-quinoline
• CAS NO: 16489-90-0
• Molecular Formula: C₁₄H₂₁NO
• Molecular Weight: 219.32264
• EINECS: 240-546-9
• Mol File: 16489-90-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 38-39 °C(Solv: hexane (110-54-3))
• Boiling Point: 295.5°Cat760mmHg
• Flash Point: 128.7°C
• Appearance: /
• Density: 0.948g/cm³
• Vapor Pressure: 0.00152mmHg at 25°C
• Refractive Index: 1.492
• PKA: 6.16±0.60(Predicted)
• CAS DataBase Reference: 6-ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline(16489-90-0)
• EPA Substance Registry System: 6-ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline(16489-90-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 16489-90-0(Hazardous Substances Data)

Usage

General Description

6-ethoxy-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline is an organic chemical compound with the molecular formula C14H21NO. It is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as an antioxidant and stabilizer in rubber and polymers. This chemical is a yellow to greenish liquid with a faint odor, and it is insoluble in water but soluble in organic solvents. It is also known by the trade name Ethoxyquin and is used in animal feeds as a preservative to prevent lipid oxidation. Additionally, it has potential implications for human health and the environment, and its use is regulated in some countries due to its potential toxicity.

InChI:InChI=1/C14H21NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-8,10,15H,5,9H2,1-4H3

Upstream product

• 91-53-2 Ethoxyquin 

Downstream Products

• 7345-50-8 8-ethoxy-4,5-dihydro-4,4-dimethyl-5H-2,3-dithiolo<5,4-c>-quinoline-1-thione 
• 72107-05-2 2,2,4-trimethyl-6-hydroxy-1,2-dihydroquinoline 

Relevant articles and documents

A new insight into ethoxyquin fate in surface waters: Stability, direct and indirect photochemical behaviour and the identification of main products

In this work, the fate of ethoxyquin (ETX), an antioxidant used as a food preservative and a pesticide, is investigated under ultraviolet and visible irradiation. The fast photolysis observed under environmentally closed conditions results in estimated degradation rates (RETXd) of 1.6 × 10-8 and 8.7 × 10-7 M s-1 at pH 2.7 and 8.0, respectively. Under our experimental conditions, the polychromatic quantum yield (RdETX) is evaluated to be 5.0 × 10-3 and 1.4 × 10-1 for the protonated and anionic forms of ETX, respectively. The effect of hydroxyl radical on ETX degradation is evaluated, and the degradation kinetics profiles suggest that transformation via hydroxyl radical can be neglected compared with direct photolysis. Structures for the main degradation products (hydrolysis, photochemical and HO?- mediated derivative) are proposed. The kinetic parameters are used as inputs in APEX software to model the degradation of ETX as a function of different scenarios in surface waters. Finally, the irradiation of ETX under sun-simulated conditions estimates the life of this compound to be ～38 s.