16498-71-8Relevant articles and documents
Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series
Magiatis, Prokopios,Melliou, Eleni,Skaltsounis, Alexios-Leandros,Mitaku, Sofia,Leonce, Stephane,Renard, Pierre,Pierre, Alain,Atassi, Ghanem
, p. 982 - 986 (2007/10/03)
The synthesis of known (3-6) and new (7-10 and 14-22) coumarins in the seselin and xanthyletin series is described. The cytotoxic activity of compounds 3-22 was carried out in vitro on L-1210 cells. The most active compounds were 9, 16, 18, and 20 in the seselin series and 10, 17, and 19 in the xanthyletin series. Structure-activity relationships are discussed.