16504-58-8

Basic information

• Product Name: 2(3H)-Furanone,4-aminodihydro-(8CI,9CI)
• Synonyms: 2(3H)-Furanone,4-aminodihydro-(8CI,9CI);2(3H)-Furanone, 4-aMinodihydro-;4-Aminodihydro-2(3H)-furanone;4-Hydroxy-3-aminobutyric acid lactone;4-Amino-dihydro-furan-2-one hydrochloride;4-Amino-dihydro-furan-2-one;4-Aminodihydrofuran-2(3H)-One Hydrochloride;4-Aminodihydrofuran-2(3H)-One Hydrochloride(WXC01359)
• CAS NO: 16504-58-8
• Molecular Formula: C4H7NO2
• Molecular Weight: 101.10388
• Product Categories: VARIOUSAMINE
• Mol File: 16504-58-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 257℃
• Flash Point: 120℃
• Appearance: /
• Density: 1.206
• PKA: 6.38±0.20(Predicted)
• CAS DataBase Reference: 2(3H)-Furanone,4-aminodihydro-(8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone,4-aminodihydro-(8CI,9CI)(16504-58-8)
• EPA Substance Registry System: 2(3H)-Furanone,4-aminodihydro-(8CI,9CI)(16504-58-8)

Safety Data

• Hazardous Substances Data: 16504-58-8(Hazardous Substances Data)

Usage

Class

Lactones (cyclic esters of hydroxy carboxylic acids)

Appearance

Colorless to yellowish liquid

Odor

Slightly sweet, fruity

Uses

Production of food and beverage flavorings

Potential interest

Pharmaceutical compound (due to biological activity)

Precautions

Potential irritant and toxic effects, should be handled with caution

Upstream product

• 87219-29-2 benzyl (3S)-5-oxotetrahydro-3-furanylcarbamate 
• 127560-92-3 (R,S)-4-benzylamino-4,5-dihydro-2(3H)-furanone 
• 98063-21-9 Emeriamine 
• 118399-28-3 (R)-4-benzyloxycarbonylamino-4,5-dihydro-2(3H)-furanone 

Downstream Products

• 1421583-00-7 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluoro-N-[(3S)-5-oxotetrahydrofuran-3-yl]benzamide 

Relevant articles and documents

Kras inhibitory cyclic peptide compound

The following were discovered: a cyclic peptide compound that interacts with Ras; and an unnatural amino acid that is useful in the production of said cyclic peptide compound. The cyclic peptide compound was also discovered to inhibit bonding between Ras and SOS. The following were additionally discovered: a specific unnatural amino acid included in said cyclic peptide compound; and a manufacturing method therefor.

N-substituted 4-amino-3,3-dipropyl-2(3H)-furanones: New positive allosteric modulators of the GABAA receptor sharing electrophysiological properties with the anticonvulsant loreclezole

1,4-Addition of benzylamine to 2(5H)-furanone followed by dialkylation of the 3-position with allylbromide gave (±)-4-benzyl-3,3-diallyl-2(3H)-furanone (8), which served as the intermediate for the synthesis of various N-substituted 4-amino-3,3-dipropyl-2