165180-41-6Relevant articles and documents
Structure-activity relationships of the 7-substituents of 5,4-'diamino- 6,8,3'-trifluoroflavone, a potent antitumor agent
Akama, Tsutomu,Ishida, Hiroyuki,Kimura, Uichiro,Gomi, Katsushige,Saito, Hiromitsu
, p. 2056 - 2067 (2007/10/03)
Recently, we reported that 5,4'-diamino-6,8,3'-trifluoroflavone (1b) exhibits potent antitumor activity against certain types of human cancer cell lines both in vitro and in vivo. Since the antiproliferative activity of 5,4'-diaminoflavon (1a), the lead c
5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent
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, (2008/06/13)
5-Aminoflavone derivatives represented by the formula (I): wherein R1 and R2 are the same or different and represent hydrogen or substituted or unsubstituted lower alkyl, X represents substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl,