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165180-44-9

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165180-44-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 165180-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,1,8 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 165180-44:
(8*1)+(7*6)+(6*5)+(5*1)+(4*8)+(3*0)+(2*4)+(1*4)=129
129 % 10 = 9
So 165180-44-9 is a valid CAS Registry Number.

165180-44-9Relevant articles and documents

Synthesis of an ethyl 6-amino-3,5-difluorosalicylate derivative by sequential regioselective directed ortho- metalation; a practical synthesis of 4',5-Diamino-3',6,8-trifluoroflavone, a potent antitumor agent

Akama, Tsutomu,Ueno, Kimihisa,Saito, Hiromitsu,Kasai, Masaji

, p. 1446 - 1450 (1997)

The multigram scale synthesis of 4',5-diamino-3'6,8-trifluoroflavone, a potent antitumor agent, is described in which regioselective introduction of a carbonyl group into the ortho-position to the amide group of 2-[2,4-difluoro-5-(pivaloylamino)phenyoxy]tetrahydropyran is achieved by using sequential direct ortho-metalations as the key step.

Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations

Akama, Tsutomu,Ishida, Hiroyuki,Shida, Yasushi,Kimura, Uichiro,Gomi, Katsushige,Saito, Hiromitsu,Fuse, Eiichi,Kobayashi, Satoshi,Yoda, Nobuyuki,Kasai, Masaji

, p. 1894 - 1900 (2007/10/03)

Recently, we reported that 5,4'-diaminoflavone (1) exhibits potent and specific growth-inhibitory activity against the estrogen receptor (ER)- positive human breast cancer cell line MCF-7. However, when compound 1 was incubated with S-9 mix, its metabolit

5-Aminoflavone derivatives, their preparation and their use as antibacterial, anti-estrogenic and/or antitumor agent

-

, (2008/06/13)

5-Aminoflavone derivatives represented by the formula (I): wherein R1 and R2 are the same or different and represent hydrogen or substituted or unsubstituted lower alkyl, X represents substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl,

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