16536-93-9

Basic information

• Product Name: Butanethioamide
• Synonyms: thiobutylamide;thiobutanamide;3-methylthiopropylamide;Thiobutyramid;thiobutyramide
• CAS NO: 16536-93-9
• Molecular Formula: C4H9NS
• Molecular Weight: 103.188
• Mol File: 16536-93-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Butanethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: Butanethioamide(16536-93-9)
• EPA Substance Registry System: Butanethioamide(16536-93-9)

Safety Data

• Hazardous Substances Data: 16536-93-9(Hazardous Substances Data)

Upstream product

• 109-74-0 propyl cyanide 
• 298-06-6 O,O-Diethyl hydrogen phosphorodithioate 
• 109-89-7 diethylamine 
• 507-09-5 tiolacetic acid 
• 53510-30-8 diethyl-n-butylamidine 
• 66365-41-1 triphenylphosphine-thiocyanogen 
• 2234-82-4 1-propylmagnesium chloride 
• 541-35-5 butanamide 

Downstream Products

• 1239497-00-7 4-(1-phenylethyl)-2-propylthiazole 
• 1239497-03-0 4-(4-chlorobenzyl)-2-propylthiazole 
• 1239497-06-3 5-(4-chlorophenyl)-2-propyl-4-((trimethylsilyl)methyl)thiazole 
• 1239497-02-9 4-benzyl-5-cyclohexenyl-2-propylthiazole 
• 1239497-01-8 4-benzyl-5-cyclopropyl-2-propylthiazole 
• 60587-86-2 2-propyl-5-thiazole-carboxaldehyde 
• 58174-44-0 S-(3-bromobenzyl) thiobutyrimidate hydrochloride 
• 303162-47-2 4-[4-(3-methylphenyl)-2-propyl-1,3-thiazol-5-yl]pyridin-2-amine 
• 109-74-0 propyl cyanide 
• 538-74-9 dibenzyl sulfide 
• 541-35-5 butanamide 

Relevant articles and documents

SUBSTITUTED THIAZOLE OR OXAZOLE P2X7 RECEPTOR ANTAGONISTS

The present invention refers to novel substituted thiazole and oxazole compounds of formula (I) having P2X7 receptor (P2X7) antagonistic properties. The compounds are useful in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans.

Substituted 1,3-thiazole compounds, their production and use

(1) A 1,3-thiazole compound of which the 5-position is substituted with a 4-pyridyl group having a substituent including no aromatic group or (2) a 1,3-thiazole compound of which the 5-position is substituted with a pyridyl group having at the position adjacent to a nitrogen atom of the pyridyl group a substituent including no aromatic group has an excellent p38 MAP kinase inhibitory activity.

5-PYRIDYL-1,3-AZOLE COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF

An optionally N-oxidized compound represented by the formula: wherein R1 represents hydrogen, hydrocarbon, heterocycle, amino, acyl, R2 represents an aromatic group, R3 represents hydrogen, pyridyl, aromatic hydrocarbon, X represents oxygen, optionally oxidized sulfur, Y represents a bond, an oxygen, optionally oxidized sulfur, a group represented by the formula NR4 (R4 represents hydrogen, hydrocarbon or acyl) and Z represents a bond or a divalent acyclic hydrocarbon, or a salt thereof has an excellent adenosine A3 receptor antagonistic activity and is used as an agent for preventing or treating diseases related to an adenosine A3 receptor. Furthermore, the compound (I) or a salt thereof has p38 MAP kinase inhibitory activity and TNF-α inhibitory activity and is used as an agent for preventing or treating diseases related to p38 MAP kinase and diseases related to TNF-α.