16546-08-0 Usage
Description
(2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide, also known as 4-methoxyphenyl ethylidene hydrazinecarbothioamide, is an organic compound with the molecular formula C10H13N3OS. It is a thiosemicarbazone derivative, containing a hydrazine group and a thiocarbonyl functional group. (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide may have potential biological activities and has been investigated for its potential pharmaceutical applications, specifically as an anti-cancer and anti-microbial agent. Its structure and properties make it a promising candidate for further research and development in the field of medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
(2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide is used as a potential anti-cancer agent for its potential to target and inhibit the growth of cancer cells. Its unique structure allows it to interact with biological targets, making it a promising candidate for the development of new cancer therapies.
Additionally, (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide is used as a potential anti-microbial agent for its ability to combat various types of bacteria and other microorganisms. Its thiosemicarbazone structure provides a versatile platform for the development of new antimicrobial drugs to address the growing issue of antibiotic resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 16546-08-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,4 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16546-08:
(7*1)+(6*6)+(5*5)+(4*4)+(3*6)+(2*0)+(1*8)=110
110 % 10 = 0
So 16546-08-0 is a valid CAS Registry Number.
16546-08-0Relevant articles and documents
Microwave-assisted Vilsmeier-Haack synthesis of Pyrazole-4-carbaldehydes
Kumari, Poonam,Sood, Sumit,Kumar, Anil,Singh, Karan
, p. 796 - 804 (2019/11/28)
The synthesis of 4-formylpyrazoles using Vilsmeier-Haack reagent is a common protocol in pyrazole chemistry. An efficient microwave-assisted synthesis of 4-formylpyrazoles by employing Vilsmeier-Haack reagent (OPC-VH) derived from phthaloyl dichloride/dimethylformamide has been described. This method offers the advantages of operational simplicity, avoiding the use of POCl3 as toxic reagents and reuse of the by-product in the preparation of phthaloyl dichloride.
VO(acac)2/H2O2 Mediated Oxidation of 1-(Thiazol-2-yl)-1H-pyrazole-4-carbaldehydes
Kumar, Anil,Kumari, Poonam,Singh, Karan,Sood, Sumit
, p. 78 - 88 (2021/01/04)
-
Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease
Rahim, Fazal,Javed, Muhammad Tariq,Ullah, Hayat,Wadood, Abdul,Taha, Muhammad,Ashraf, Muhammad,Qurat-Ul-Ain,Khan, Muhammad Anas,Khan, Fahad,Mirza, Salma,Khan, Khalid M.
, p. 106 - 116 (2015/09/02)
A series of thirty (30) thiazole analogs were prepared, characterized by 1H NMR, 13C NMR and EI-MS and evaluated for Acetylcholinesterase and butyrylcholinesterase inhibitory potential. All analogs exhibited varied butyrylcholinester