16571-59-8

Basic information

• Product Name: 1-Benzyl-3-[2-(4-pyridyl)ethyl]-1H-indole
• Synonyms: 1-Benzyl-3-[2-(4-pyridyl)ethyl]-1H-indole
• CAS NO: 16571-59-8
• Molecular Formula: C₂₂H₂₀N₂
• Molecular Weight: 312.41
• Mol File: 16571-59-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 225-230 °C(Press: 0.3 Torr)
• Appearance: /
• Density: 1.08±0.1 g/cm3(Predicted)
• PKA: 6.03±0.10(Predicted)
• CAS DataBase Reference: 1-Benzyl-3-[2-(4-pyridyl)ethyl]-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-3-[2-(4-pyridyl)ethyl]-1H-indole(16571-59-8)
• EPA Substance Registry System: 1-Benzyl-3-[2-(4-pyridyl)ethyl]-1H-indole(16571-59-8)

Safety Data

• Hazardous Substances Data: 16571-59-8(Hazardous Substances Data)

Upstream product

• 100-43-6 4-vinylpyridine 
• 3377-71-7 N-benzylindole 

Downstream Products

• 21199-40-6 4-[2-(1-benzyl-indol-3-yl)-ethyl]-1-(3-trimethylammonio-propyl)-pyridinium; dibromide 
• 22547-46-2 1-benzyl-3-(2-piperidin-4-yl-ethyl)-indole 

Relevant articles and documents

3-(4-Piperidinylalkyl)indoles, Selective Inhibitors of Neuronal 5-Hydroxytryptamine Uptake

A series 3-(4-piperidinylalkyl)indoles was synthesized and tested as uptake inhibitors of biogenic amines.Some of these compounds are potent and very selective in blocking the 5-hydroxytryptamine (5-HT) uptake, as evidenced by biochemical data and behavioral tests.A discussion on structure-activity relationships is given.The most interesting member of the series, indalpine, 3-indole (1), was selected for clinical studies.