16574-54-2

Basic information

• Product Name: Methanone, [4-(dimethylamino)phenyl](4-fluorophenyl)-
• CAS NO: 16574-54-2
• Molecular Formula: C15H14FNO
• Molecular Weight: 243.281
• Mol File: 16574-54-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methanone, [4-(dimethylamino)phenyl](4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [4-(dimethylamino)phenyl](4-fluorophenyl)-(16574-54-2)
• EPA Substance Registry System: Methanone, [4-(dimethylamino)phenyl](4-fluorophenyl)-(16574-54-2)

Safety Data

• Hazardous Substances Data: 16574-54-2(Hazardous Substances Data)

Upstream product

• 345-92-6 4,4'-Difluorobenzophenone 
• 80-70-6 N,N,N',N'-tetramethylguanidine 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 1414852-71-3 MIDA ((4-fluorophenyl)oxomethyl)boronate 
• 39768-80-4 (4-Dimethylamino-phenyl)-(4-fluoro-phenyl)-methanol 

Downstream Products

• 38695-24-8 4-(4-fluorobenzyl)-N,N-dimethylaniline 

Relevant articles and documents

Acylboronates in polarity-reversed generation of acyl palladium(II) intermediates

We report a catalytic cross-coupling process between aryl (pseudo)halides and boron-based acyl anion equivalents. This mode of acylboronate reactivity represents polarity reversal, which is supported by the observation of tetracoordinated boronate and acyl palladium(II) species by 11B, 31P NMR, and mass spectrometry. A broad scope of aliphatic and aromatic acylboronates has been examined, as well as a variety of aryl (pseudo)halides.

Unusual aminations with tetramethylguanidine

Heating activated halobenzenes with 1,1,3,3-tetramethylguanidine affords mixtures of dimethylaminobenzenes and 2-aryl-1,1,3,3-tetramethylguanidines.