16619-96-8

Basic information

• Product Name: 1,2,3-triphenyl-2H-isoindole
• CAS NO: 16619-96-8
• Molecular Weight: 345.444
• Mol File: 16619-96-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,3-triphenyl-2H-isoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-triphenyl-2H-isoindole(16619-96-8)
• EPA Substance Registry System: 1,2,3-triphenyl-2H-isoindole(16619-96-8)

Safety Data

• Hazardous Substances Data: 16619-96-8(Hazardous Substances Data)

Upstream product

• 36149-34-5 2,3-diphenyl-2,3-dihydroisoindol-1-one 
• 591-51-5 phenyllithium 
• 119-61-9 benzophenone 
• 1586-73-8 tris(trimethylsilyl)amine 

Downstream Products

• 123777-73-1 1,2,3-triphenyl-2,3-dihydro-1H-1,3-epidioxido-isoindole 

Relevant articles and documents

UEBER DIE SI-N-BINDUNG XLIV. DIE UMSETZUNG VON BENZOPHENON MIT BIS- UND TRIS(TRIMETHYLSILYL)AMIN

1,1,3-Triphenyl-1H-isoindole (I) is obtained in yields up to 66percent by reacting benzophenone with tris(trimethylsilyl)amine or with bis(trimethylsilyl)amine and chlorotrimethylsilane in the presence of catalytic amounts of a Lewis acid at 230-280 deg C in a sealed tube or with equimolar amounts of a Lewis acid at 210 deg C without using a sealed tube.At temperatures above 280 deg C the same reactions yiels mixtures of I with 1,2,3-triphenyl-2H-isoindole (II), whose fraction can reach 25percent of the isoindole mixture.Mechanistic investigations on the new isoindole synthesis indicated, that azaallenium cations are involved as intermediates.