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166194-08-7

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166194-08-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 166194-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,1,9 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 166194-08:
(8*1)+(7*6)+(6*6)+(5*1)+(4*9)+(3*4)+(2*0)+(1*8)=147
147 % 10 = 7
So 166194-08-7 is a valid CAS Registry Number.

166194-08-7Relevant articles and documents

Synthesis of 3,5-disubstituted-1,2-dioxolanes: access to analogues of mycangimycin and some rearrangement products

Nguyen, Thuy Linh,Ferrié, Laurent,Figadère, Bruno

, p. 5286 - 5289 (2016)

Mycangimycin is a eicosa-heptenic acid containing an unprecedented 3,5-disubstituted-1,2-dioxolane ring with promising anti-fungal and antimalarial activity. Most reported methods to prepare 1,2-dioxolanes are targeting 3,3,5,5-tetrasubstituted or 3,3,5-trisubstituted 1,2-dioxolanes. Thus, some methods for synthesizing these unusual 3,5-disubstituted 1,2-dioxolanes were investigated. The most promising approach was the use of a Kulinkovich reaction followed by an oxidative ring opening of the cyclopropanol with Co(acac)2to reach the peroxy-hemiketal structure. Successive triflic acid mediated silane reduction of the corresponding peroxy-hemiketal afforded the expected 3,5-disubstituted-1,2-dioxolane ring. Through our studies, some unprecedented rearrangements of 1,2-dioxolane rings were observed, which will be discussed in this Letter. Finally, two saturated analogues of mycangimycin were synthesized.

SULFONAMIDE COMPOUNDS HAVING TNAP INHIBITORY ACTIVITY

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Page/Page column 112; 171; 172; 173, (2018/07/29)

The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.

Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds - Synthesis and in vitro metabolism of deuterated derivatives of dronedadrone

Schofield, Joseph,Brasseur, Denis,De Bruin, Beatrice,Vassal, Thierry,Klieber, Sylvie,Arabeyre, Catherine,Bourrie, Martine,Sadoun, Freddy,Fabre, Gerard

, p. 504 - 512 (2014/03/21)

The synthesis and in vitro metabolism studies of a family of specifically deuterated derivatives of dronedarone are described. Metabolic stability and clearance of the parent compound are not sensitive to deuterium substitution, irrespective of the position of the heavy label. Copyright

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