166271-34-7

Basic information

• Product Name: Benzenesulfonamide, N-(3-chloro-2-quinoxalinyl)-
• Synonyms: N-(3-chloro-2-quinoxalinyl)benzenesulfonamide;N-(3-chloroquinoxalin-2-yl)benzenesulfonamide
• CAS NO: 166271-34-7
• Molecular Formula: C14H10ClN3O2S
• Molecular Weight: 319.771
• Mol File: 166271-34-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 489.1±55.0 °C(Predicted)
• Density: 1.515±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenesulfonamide, N-(3-chloro-2-quinoxalinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(3-chloro-2-quinoxalinyl)-(166271-34-7)
• EPA Substance Registry System: Benzenesulfonamide, N-(3-chloro-2-quinoxalinyl)-(166271-34-7)

Safety Data

• Hazardous Substances Data: 166271-34-7(Hazardous Substances Data)

Upstream product

• 98-10-2 benzenesulfonamide 
• 2213-63-0 2,3-dichloroquinoxaline 

Downstream Products

• 325815-76-7 N-(3-(4-fluorophenylamino)quinoxalin-2-yl)benzenesulfonamide 
• 531-46-4 5,12-dihydroquinoxalino[2,3-b]quinoxaline 

Relevant articles and documents

METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES

The present invention provides a new synthesis for preparing N-(3-amino-quinoxalin-2-yl)-sulfonamides of general formulae (I) or (I') and intermediates sulfonamides of formula (II) or (II'):

METHODS OF USING PI3K AND MEK MODULATORS

The invention provides methods of treating cancer with a combination of compounds which inhibit kinases, more specifically MEK and PI3K.

PYRAZINE DERIVATIVES AND USE AS PI3K INHIBITORS

The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.