166324-34-1

Basic information

• Product Name: 4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one
• Synonyms: 4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one
• CAS NO: 166324-34-1
• Molecular Weight: 309.43
• Mol File: 166324-34-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one(166324-34-1)
• EPA Substance Registry System: 4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one(166324-34-1)

Safety Data

• Hazardous Substances Data: 166324-34-1(Hazardous Substances Data)

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 96-17-3 2-Methylbutyraldehyde 
• 1027595-29-4 2-Chloro-N-(4-methoxy-benzyl)-N-((E)-2-methyl-but-1-enyl)-2-methylsulfanyl-acetamide 

Downstream Products

• 166324-35-2 4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methylpyrrolidin-2-one 
• 77-67-8 ethosuximide 
• 166324-36-3 4-ethyl-1-(4-methoxybenzyl)-4-methylpyrrolidine-2,5-dione 

Relevant articles and documents

Uncatalyzed Cationic Olefin Cyclizations of N-Vinylic α-Chloro-α-thioacetamides. Formation of β- and γ-Lactams

N-Vinylic α-chloro-α-thioacetamides were found to cyclize without a catalyst in two different manners depending upon the nature of the substituents at the terminus of the N-vinylic bond.Thus, bis(phenylthio)-substituted enamides 8a-c cyclized in a 4-exo-trig manner to give 4-methylene-β-lactams 10a-c, whereas mono(phenylthio)-, monophenyl-, and dialkyl-substituted congeners 23a,b, 28, and 38 cyclized in a 5-endo-trig manner to give γ-lactams 26a,b, 30, and 39, respectively.The product 38 was transformed into an anticonvulsant agent ethosuximide (42).