16635-71-5

Basic information

• Product Name: (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one
• Synonyms: (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one
• CAS NO: 16635-71-5
• Molecular Weight: 282.296
• Mol File: 16635-71-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one(16635-71-5)
• EPA Substance Registry System: (E)-3-(benzo[d][1,3]dioxol-5-yl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one(16635-71-5)

Safety Data

• Hazardous Substances Data: 16635-71-5(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 

Relevant articles and documents

Discovery of 2′-hydroxychalcones as autophagy inducer in A549 lung cancer cells

A series of 2′-hydroxychalcone derivatives was synthesized and the effects of all the compounds on growth of A549 lung cancer cell were investigated. The results showed that all compounds had inhibitory effects on the growth of A549 lung cancer cells and compound 2-7 possessed the highest growth inhibitory effect and induced autophagy of A549 lung cancer cells.

CDK inhibitors having flavone structure

The present invention relates to a novel flavone derivative, pharmaceutically acceptable salt, hydrate, solvate and isomer thereof which is useful as an inhibitor against Cyclin Dependent Kinase (CDK), a process for preparation thereof, and a composition of anti-cancer agent or agent for treating neurodegenerative disease comprising this compound as an active ingredient.