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166372-23-2

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166372-23-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 166372-23-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,3,7 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 166372-23:
(8*1)+(7*6)+(6*6)+(5*3)+(4*7)+(3*2)+(2*2)+(1*3)=142
142 % 10 = 2
So 166372-23-2 is a valid CAS Registry Number.

166372-23-2Relevant articles and documents

Synthesis and biological activity of phosphoglycolipids from Thermus thermophilus

Fujimoto, Yukari,Mitsunobe, Kunihiro,Fujiwara, Satoko,Mori, Motoko,Hashimoto, Masahiro,Suda, Yasuo,Kusumoto, Shoichi,Fukase, Koichi

supporting information, p. 5034 - 5041 (2013/08/23)

An extreme thermophile, Thermus thermophilus, has very unique glycolipids on the cell surface. The acidic immunostimulatory phosphoglycolipid of T. thermophilus was synthesized for the first time, with newly developed glycosylation methods using 3-nitropyridyl (3NPy) and 4,6-dimethoxy-1,3,5- triazin-2-yl (DMT) glycosides as glycosyl donors. The analogues of the phosphoglycolipid, which include a diastereomer possessing the opposite configuration at the diacyl glycerol moiety, were also synthesized. The biological activities of the synthesized compounds were elucidated with cytokine inductions (IL-6 and TNF-α). A synthetic phosphoglycolipid with a natural-type diacyl glycerol configuration showed apparent immunostimulatory activity, whereas its diastereomer did not. The present study revealed that the configuration at the diacyl glycerol moiety of the phosphoglycolipids is important for immunostimulation, suggesting the existence of the particular receptor/recognizing protein that can recognize the stereochemistry of the glycerol part.

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