166398-41-0Relevant articles and documents
A palladium/norbornene cooperative catalysis to access N-containing bridged scaffolds
Gao, Qianwen,Liu, Ze-Shui,Hua, Yu,Li, Lisha,Cheng, Hong-Gang,Cong, Hengjiang,Zhou, Qianghui
supporting information, p. 8816 - 8819 (2019/07/31)
A palladium/norbornene cooperative catalysis promoted annulation involving an ortho-C-H amination and intramolecular Heck cascade between aryl iodides and functionalized amination reagents is reported, thereby providing a highly convergent access to the u
AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS
-
Page/Page column 15, (2015/11/10)
The present invention relates to azaindole acetic acid derivatives of formula (I), (I) wherein R1 and R2 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.
N,N-Dimethyl-[9-(arylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amines as novel, potent and selective 5-HT6 receptor antagonists
Nirogi, Ramakrishna V. S.,Konda, Jagadishu Babu,Kambhampati, Ramasastry,Shinde, Anil,Bandyala, Thrinath Reddy,Gudla, Parandhama,Kandukuri, Kiran Kumar,Jayarajan, Pradeep,Kandikere, Vishwottam,Dubey, P. K.
supporting information, p. 6980 - 6985,6 (2020/09/02)
The design, synthesis and SAR of novel tetrahydrocarbazole derivatives having 5-HT6 receptor antagonist activity is presented. The racemic compound 15e was found to possess desirable pharmacokinetic properties, adequate brain penetration and activity in animal models of cognition.