16644-05-6

Basic information

• Product Name: Heptane-4,4-dicarboxylic acid dimethyl ester
• Synonyms: Dipropylmalonic acid dimethyl ester;Heptane-4,4-dicarboxylic acid dimethyl ester;Dimethyl 2,2-Dipropylmalonate;Propanedioic acid, dipropyl-, dimethyl ester;Dimethyl 2,2-Dipropylmalonate(WX618468)
• CAS NO: 16644-05-6
• Molecular Formula: C11H20O4
• Molecular Weight: 216.27
• Mol File: 16644-05-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 233.2°C at 760 mmHg
• Flash Point: 100.3°C
• Appearance: /
• Density: 0.996g/cm³
• Vapor Pressure: 0.0565mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: Heptane-4,4-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Heptane-4,4-dicarboxylic acid dimethyl ester(16644-05-6)
• EPA Substance Registry System: Heptane-4,4-dicarboxylic acid dimethyl ester(16644-05-6)

Safety Data

• Hazardous Substances Data: 16644-05-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H20O4/c1-5-7-11(8-6-2,9(12)14-3)10(13)15-4/h5-8H2,1-4H3

Upstream product

• 106-94-5 propyl bromide 
• 108-59-8 malonic acid dimethyl ester 
• 35357-77-8 dimethyl bisallylmalonate 
• 18795-82-9 2-propylidene malonic acid dimethyl ester 

Downstream Products

• 1636-27-7 di-n-propylmalonic acid 
• 22632-59-3 methyl 2-propylvalerate 
• 99-66-1 valproic acid 
• 18295-59-5 2-propylpentanal 

Relevant articles and documents

Preparation method and application of Grignard reagent

The invention relates to a preparation method and application of a Grignard reagent, the Grignard reagent is obtained by treating a halide with a structural formula as a raw material with magnesium inan organic solvent, X is a halogen atom and is selected from Cl, Br and I, R2 is an alkyl or aryl group containing 2-9 carbon atoms. The Grignard reagent is mainly applied to a synthetic process of dimopidol and hydrochloride thereof, and is used for introducing an alkyl side chain. The whole synthetic process of dimopidol and hydrochloride thereof is safe and efficient, each step of reaction operation is simple and safe, and the reaction yield is high so that industrial production can be realized.

Mechanism of cycloisomerisation of 1,6-heptadienes catalysed by [(tBuCN)2PdCl2]: Remarkable influence of exogenous and endogenous 1,6- And 1,5-diene ligands

The mechanism of the highly regioselective cycloisomerisation of dimethyl hept-1,6-dienyl-4,4-dicarboxylate (1) by a neutral pre-catalyst, [(tBuCN) 2PdCl2] (8), to generate dimethyl 3,4-dimethylcyclopent-2- ene-1,1-dicarboxylate (3)