166442-37-1 Usage
Description
5Acetamido-2carboxy-4-dimethylamino-2-hydroxybenzophenone is a chemical compound that serves as an intermediate in the synthesis of rhodamine derivatives. It is characterized by its brown plate-like appearance and is known for its role in the preparation of fluorescent labels.
Uses
Used in Chemical Synthesis:
5Acetamido-2carboxy-4-dimethylamino-2-hydroxybenzophenone is used as an intermediate for the preparation of rhodamine derivatives, which are essential in the creation of fluorescent labels. These labels are crucial in various applications, including biological research, medical diagnostics, and imaging techniques.
Used in Biomedical Research:
In the field of biomedical research, 5Acetamido-2carboxy-4-dimethylamino-2-hydroxybenzophenone is used as a component in the development of fluorescent markers. These markers are vital for tracking and visualizing cellular processes, protein interactions, and other biological phenomena, contributing to a better understanding of complex biological systems.
Used in Diagnostics and Imaging:
5Acetamido-2carboxy-4-dimethylamino-2-hydroxybenzophenone plays a significant role in the production of fluorescent labels for medical diagnostics and imaging. These labels are employed in various techniques, such as fluorescence microscopy and flow cytometry, to detect and monitor diseases, assess treatment efficacy, and study cellular functions in a clinical setting.
Used in Material Science:
In material science, 5Acetamido-2carboxy-4-dimethylamino-2-hydroxybenzophenone can be utilized in the development of advanced materials with specific optical properties. These materials can be applied in various industries, such as optoelectronics, where they can be used to create light-emitting devices or improve the efficiency of solar cells.
Overall, 5Acetamido-2carboxy-4-dimethylamino-2-hydroxybenzophenone is a versatile compound with applications in chemical synthesis, biomedical research, diagnostics, imaging, and material science, primarily due to its role in the preparation of rhodamine derivatives and fluorescent labels.
Check Digit Verification of cas no
The CAS Registry Mumber 166442-37-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,4,4 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 166442-37:
(8*1)+(7*6)+(6*6)+(5*4)+(4*4)+(3*2)+(2*3)+(1*7)=141
141 % 10 = 1
So 166442-37-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H18N2O5/c1-10(21)19-11-4-6-13(18(24)25)15(8-11)17(23)14-7-5-12(20(2)3)9-16(14)22/h4-9,22H,1-3H3,(H,19,21)(H,24,25)
166442-37-1Relevant articles and documents
Synthesis and Characterisation of Pure Isomers of Iodoacetamidotetramethylrhodamine
Corrie, John E. T.,Craik, James S.
, p. 2967 - 2974 (2007/10/02)
The isomeric benzoylnitrobenzoate esters 5 and 6, prepared by condensation of 4-nitrophthalic anhydride and 3-(dimethylamino)phenol followed by esterification, were separated by fractional crystallisation and their structures assigned by NOE difference spectroscopy.Reduction of the nitro group in each compound followed by acetylation and ester hydrolysis gave the isomeric acetamido acids 7 and 8, which were efficiently condensed with 3-(diemthylamino)phenol in the presence of trimethylsilyl polyphosphate to give the acetamidorhodamines 9 and 10, respectively.These compounds were converted by standard means into the pure 6- and 5-(iodoacetamido)tetramethylrhodamines 1 and 2.The visible spectroscopic properties of the compounds were examined and accurate extinction determined.
