166663-45-2

Basic information

• Product Name: 4-(2-phenylethynyl)phenyl trifluoromethanesulfonate
• Synonyms: 4-(2-phenylethynyl)phenyl trifluoromethanesulfonate
• CAS NO: 166663-45-2
• Molecular Weight: 326.296
• Mol File: 166663-45-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-(2-phenylethynyl)phenyl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-phenylethynyl)phenyl trifluoromethanesulfonate(166663-45-2)
• EPA Substance Registry System: 4-(2-phenylethynyl)phenyl trifluoromethanesulfonate(166663-45-2)

Safety Data

• Hazardous Substances Data: 166663-45-2(Hazardous Substances Data)

Upstream product

• 106-48-9 4-chloro-phenol 
• 29540-84-9 4-chlorophenyl trifluoromethanesulfonate 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 1357115-38-8 4-((trimethylsilyl)ethynyl)phenyl trifluoromethanesulfonate 
• 108-90-7 chlorobenzene 
• 108-86-1 bromobenzene 
• 2926-30-9 sodium triflate 
• 66107-30-0 4-bromophenyl trifluoromethanesulfonate 
• 536-74-3 phenylacetylene 
• 6738-06-3 phenylethynylmagnesium bromide 
• 839686-54-3 4-<<-tert-butyldimethylsiloxy)phenyl>ethynyl>benzene 

Downstream Products

• 1026638-10-7 4-(4-Phenylethynyl-phenylethynyl)-benzoic acid 2,4,5-trichloro-phenyl ester 
• 1027986-99-7 4-(4-Phenylethynyl-phenylethynyl)-benzoic acid 
• 166663-41-8 methyl 4-<<4'-(phenylethynyl)phenyl>ethynyl>benzoate 

Relevant articles and documents

Bismuth-Catalyzed Oxidative Coupling of Arylboronic Acids with Triflate and Nonaflate Salts

Herein we present a Bi-catalyzed cross-coupling of arylboronic acids with perfluoroalkyl sulfonate salts based on a Bi(III)/Bi(V) redox cycle. An electron-deficient sulfone ligand proved to be key for the successful implementation of this protocol, which allows the unusual construction of C(sp2)-O bonds using commercially available NaOTf and KONf as coupling partners. Preliminary mechanistic studies as well as theoretical investigations reveal the intermediacy of a highly electrophilic Bi(V) species, which rapidly eliminates phenyl triflate.

Zinc chloride-promoted aryl bromide-alkyne cross-coupling reactions at room temperature

(Chemical Equation Presented) Substoichiometric amounts of ZnCl2 promote the room temperature, Pd/P(t-Bu)3-catalyzed cross-coupling of aryl bromides with alkynes. Pd(I) dimer 1 is demonstrated to be a particularly active precatalyst for this reaction. The reaction is general for a wide variety of aryl bromides.

Dichloro[(2-dimethylamino)propyldiphenylphosphine]palladium(II) (PdCl2(alaphos)): An efficient catalyst for cross-coupling of aryl triflates with alkynyl grignard reagents

Dichloro[(2-dimethylamino)propyldiphenylphosphine]palladium (PdCl2(alaphos)) was found to be much more effective as catalyst than other palladium complexes for cross-coupling of aryl triflates with alkynyl Grignard reagents. Reaction of bromoaryl triflates with alkynyl Grignard reagents in the presence of PdCl2(alaphos) catalyst gave high yields of alkynyl arene bromides, which were formed by selective replacement of triflate by alkynyl group.