1667-04-5

Basic information

• Product Name: 2-CHLOROMESITYLENE
• Synonyms: 2,4,6-Trimethylchlorobenzene;2,4,6-Trimethylmonochlorobenzene;Benzene,2-chloro-1,3,5-trimethyl-;Mesitylene, 2-chloro-;Mesitylene,2-chloro-;1-CHLORO-2,4,6-TRIMETHYLBENZENE;2-CHLORO-1,3,5-TRIMETHYLBENZENE;2-CHLOROMESITYLENE
• CAS NO: 1667-04-5
• Molecular Formula: C₉H₁₁Cl
• Molecular Weight: 154.64
• Mol File: 1667-04-5.mol
• Article Data: 45

Chemical Properties

• Melting Point: -43.35°C (estimate)
• Boiling Point: 204-206°C
• Flash Point: 76.8 °C
• Appearance: /
• Density: 1.05
• Refractive Index: 1.5212
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLOROMESITYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROMESITYLENE(1667-04-5)
• EPA Substance Registry System: 2-CHLOROMESITYLENE(1667-04-5)

Safety Data

• Hazardous Substances Data: 1667-04-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 116, p. 8414, 1994 DOI: 10.1021/ja00097a078

Upstream product

• 527-60-6 Mesitol 
• 3453-83-6 mesitylene sulfonic acid 
• 27876-29-5 acetic acid-(2,4,6,N-tetrachloro-anilide) 
• 64-19-7 acetic acid 
• 108-67-8 1,3,5-trimethyl-benzene 
• 88-05-1 2,4,6-trimethylaniline 
• 111149-52-1 4-methylchlorobenzene-2,6-dicarboxaldehyde 
• 102626-21-1 chloro-6-methylbenzene-2,4-dicarboxaldehyde 
• 102626-20-0 2-chlorobenzene-1,3,5-tricarboxaldehyde 
• 93201-55-9 2,4,6-trimethylphenyl fluoroformate 
• 5707-04-0 Phenylselenyl chloride 
• 938-18-1 mesitylene-2-carboxylic acid chloride 
• 7693-47-2 2,4,6-trimethylphenyl carbonochloridate 
• 10026-13-8 phosphorus pentachloride 

Downstream Products

• 5324-68-5 1,3,5-trichloro-2,4,6-trimethylbenzene 
• 67396-77-4 2-chloro-1,3,5-trimethyl-4-nitrobenzene 
• 57386-83-1 1,3-dichloro-2,4,6-trimethylbenzene 
• 628302-82-9 2-chloro-1,3,5-tris-trichloromethyl-benzene 
• 56961-24-1 benzene-1,3,5-tricarboxylic acid chloride 
• 67396-86-5 2-Chloro-3,5-dimethylbenzylacetat 
• 67396-84-3 4-Chloro-3,5-dimethylbenzylacetat 
• 67396-85-4 1,5-Bisacetoxymethyl-2-chloro-3-methylbenzol 
• 26583-85-7 2-bromo-4-chloro-1,3,5-trimethylbenzene 
• 41571-69-1 2-Chlor-4,6-diiod-1,3,5-trimethylbenzol 
• 108244-61-7 1-chloro-2,4,6-trimethyl-3,5-dinitro-benzene 
• 67396-78-5 4-Chloro-1,3,5-trimethyl-4-nitrocyclohexa-2,5-dienylacetat 
• 4482-03-5 bimesityl 
• 42797-68-2 1-(2,4,6-trimethylphenyl)-2-propanone 

Relevant articles and documents

In situ Generation of Hypervalent Iodine Reagents for the Electrophilic Chlorination of Arenes

Efficient metal-free methods for the electrophilic chlorination of arenes using PIFA and simple chlorine sources are reported. The in situ formation of PhI(Cl)OCOCF3 from PIFA and KCl is proposed, which resulted in a chlorinating species for moderately activated arenes. Moreover, the in situ formation of PhICl2 from PIFA and TMSCl resulted in an excellent approach for the chlorination of a great variety of arenes (20 examples) in high yields, even when working on a multigram scale.

R4NHal/NOHSO4: A Usable System for Halogenation of Isoxazoles, Pyrazoles, and beyond

A new convenient and versatile halogenating system (R4NHal/NOHSO4), giving straightforward and general access to halogenated 3,5-diaryl- and alkylarylisoxazoles, pyrazoles and electron-rich benzenes from the corresponding scaffolds, is suggested. The method provides excellent regioselectivity, scalability to the gram scale, and a broad scope for both aromatics and halogens. A three-step, one-pot reaction protocol was developed, and a series of 3,5-diaryl-4-haloisoxazoles has been efficiently synthesized from 1,2-diarylcyclopropanes under suggested nitrosating-halogenating conditions.

Rigid heterocyclic compound, preparation method and application thereof, phosphine-containing sulfonamide compound and preparation method thereof

The invention relates to the field of organic synthesis, in particular to a rigid heterocyclic compound with sulfonyl and pentavalent phosphorus-nitrogen double bonds as shown in the following generalformula (I) and a preparation method and application th