16677-35-3

Basic information

• Product Name: N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycine methyl ester
• Synonyms: N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycine methyl ester
• CAS NO: 16677-35-3
• Molecular Weight: 476.529
• Mol File: 16677-35-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycine methyl ester(16677-35-3)
• EPA Substance Registry System: N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycine methyl ester(16677-35-3)

Safety Data

• Hazardous Substances Data: 16677-35-3(Hazardous Substances Data)

Upstream product

• 86827-18-1 N-benzyloxycarbonyl-O-benzyl-L-tyrosine 
• 5680-79-5 glycine ethyl ester hydrochloride 

Downstream Products

• 51952-34-2 (S)-2-(2-(((benzyloxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanamido)acetic acid 
• 145763-38-8 N-benzyloxycarbonyl-O-benzyl-(S)tyrosyl-glycyl-glycyl-(Z)dehydrophenylalanyl(S)leucine methyl ester 
• 145763-53-7 C₄₄H₄₉⁽²⁾H₂N₅O₉ 
• 85541-25-9 N-benzyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine methyl ester 
• 96914-93-1 N-<<<(tyrosylglycyl)amino>methyl>hydroxyphosphinyl>phenylalanylleucine disodium salt 
• 96914-85-1 C₅₆H₆₂N₅O₁₀P 
• 51952-35-3 Z-Tyr(CH₂Ph)-Gly-NH-NH-Boc 

Relevant articles and documents

DIASTEREOSELECTIVE HYDROGENATION OF MONODEHYDRO ENKEPHALINS CONTROLLED BY CHIRAL RHODIUM CATALYSTS

Protected (Z)dehydrophenylalanyl-Leu-enkephalin, (Z)dehydrotyrosyl-Leu-enkephalin and (Z)dehydrotyrosyl-(R)Ala2-Leu-enkephalin, have been synthesized.These compounds have been hydrogenated to give protected Leu-enkephalins in the presence of various chiral rhodium complexes.Deprotection of the product gave Leu-enkephalins or epimers, ytterbium in liquid ammonia allows smooth deprotection of NHCBz or OTs groups on small amounts of peptides.Strong stereocontrol could be achieved by suitable choice of the chiral catalyst.This method has good potential for stereospecific labelling of enkephalins and other small peptides.