16682-12-5 Usage
Description
D-Ornithine monohydrochloride is the monohydrochloride form of D-Ornithine, a non-proteinogenic amino acid that plays a role in the urea cycle by aiding in the splitting off of urea from arginine. It is a white to off-white crystalline powder and has been found to attenuate fatigue by increasing the efficiency of energy consumption and promoting the excretion of ammonia.
Uses
1. Used in Stress Response Studies:
D-Ornithine monohydrochloride is used as a stress attenuator for reducing the stress response in neonatal chicks under acute stressful conditions. It achieves this by being administered intracerebroventricularly, which helps in managing stress-related effects.
2. Used in Fatigue Reduction:
D-Ornithine monohydrochloride is used as a fatigue-reducing agent, as it increases the efficiency of energy consumption and promotes the excretion of ammonia, thus helping to alleviate fatigue in individuals.
3. Used in the Urea Cycle:
D-Ornithine monohydrochloride is used as a component in the urea cycle, where it contributes to the splitting off of urea from arginine, playing a crucial role in the detoxification process of the body.
4. Used in Pharmaceutical Applications:
D-Ornithine monohydrochloride can be used as an active pharmaceutical ingredient due to its involvement in various biological processes, including stress response and fatigue reduction. It may be formulated into medications targeting these areas for therapeutic use.
5. Used in Nutritional Supplements:
Given its role in energy consumption and ammonia excretion, D-Ornithine monohydrochloride can be used as an ingredient in nutritional supplements aimed at enhancing physical performance and recovery, particularly for athletes and individuals engaged in strenuous activities.
6. Used in Research and Development:
D-Ornithine monohydrochloride can be utilized in research and development for studying its effects on stress response, fatigue, and other related physiological processes. This can lead to the discovery of new applications and potential therapeutic uses in medicine.
References
https://pubchem.ncbi.nlm.nih.gov/compound/D-ornithine
https://en.wikipedia.org/wiki/Ornithine
Biochem/physiol Actions
D-Ornithine cleave proteins at cysteine residues.
Check Digit Verification of cas no
The CAS Registry Mumber 16682-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,8 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16682-12:
(7*1)+(6*6)+(5*6)+(4*8)+(3*2)+(2*1)+(1*2)=115
115 % 10 = 5
So 16682-12-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1/t4-/m1/s1
16682-12-5Relevant articles and documents
Highly enantioselective synthesis of non-natural aliphatic α-amino acids via asymmetric hydrogenation
Ji, Jianjian,Chen, Caiyou,Cai, Jiayu,Wang, Xinrui,Zhang, Kai,Shi, Liyang,Lv, Hui,Zhang, Xumu
supporting information, p. 7624 - 7627 (2015/07/15)
By employing a rhodium-Duanphos complex as the catalyst, β-alkyl (Z)-N-acetyldehydroamino esters were smoothly hydrogenated in a highly efficient and enantioselective way. Excellent enantioselectivities together with excellent yields were achieved for a series of substrates. An efficient approach for the synthesis of the intermediate of the orally administered anti-diabetic drugs Alogliptin and Linagliptin in the DPP-4 inhibitor class was also developed.
