16692-58-3

Basic information

• Product Name: 2-(pent-1'-enyl)benzoic acid
• Synonyms: 2-(pent-1'-enyl)benzoic acid
• CAS NO: 16692-58-3
• Molecular Weight: 190.242
• Mol File: 16692-58-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 328.3±21.0 °C(Predicted)
• Density: 1.081±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(pent-1'-enyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(pent-1'-enyl)benzoic acid(16692-58-3)
• EPA Substance Registry System: 2-(pent-1'-enyl)benzoic acid(16692-58-3)

Safety Data

• Hazardous Substances Data: 16692-58-3(Hazardous Substances Data)

Usage

General Description

2-(pent-1'-enyl)benzoic acid, also known as o-(1-penten-1-yl)benzoic acid, is a chemical compound with the molecular formula C14H16O2. It is a derivative of benzoic acid with a pentenyl group attached to the second position of the benzene ring. 2-(pent-1'-enyl)benzoic acid has potential applications in the pharmaceutical and chemical industries, and it is also used as a building block in the synthesis of various organic compounds. Its properties and behavior in different environments, as well as its potential biological activity, make it a subject of interest for further research and exploration.

Upstream product

• 1009-14-9 phenyl butyl ketone 
• 32730-83-9 1-(2-iodophenyl)pentan-1-one 
• 144-62-7 oxalic acid 
• 87-24-1 ethyl 2-methylbenzoate 
• 124-38-9 carbon dioxide 
• 16692-57-2 (E)-1-bromo-2-(pent-1-enyl)benzene 
• 119-67-5 o-carboxybenzaldehyde 
• 95330-34-0 methyl (E)-2-(pent-1-en-1-yl)benzoate 
• 4122-56-9 methyl o-formylbenzoate 
• 1194-57-6 2-thiophthalide 
• 123-72-8 butyraldehyde 

Downstream Products

• 95330-34-0 methyl (E)-2-(pent-1-en-1-yl)benzoate 
• 95330-38-4 (E)-2-pent-1-enylbenzyl alcohol 
• 866314-57-0 (E)-2-[2-(1-n-pentenyl)-benzyl]-3-oxobutanoic acid ethyl ester 
• 866314-65-0 2-Diazo-3-[((E)-2-pent-1-enyl)-phenyl]-propionic acid ethyl ester 
• 81944-09-4 Z-ligustilide 

Relevant articles and documents

Palladium-catalyzed: Ortho -halogen-induced deoxygenative approach of alkyl aryl ketones to 2-vinylbenzoic acids

The 2-vinylbenzoic acids have wide applications in the field of polymer chemistry and are key precursors for the synthesis of important bioactive molecules. Herein, an ortho-halogen-induced deoxygenative approach for the generation of 2-vinylbenzoic acids from alkyl aryl ketones by palladium catalysis is discovered and explored. This approach requires no base or stoichiometric additives and can be carried out through a simple one-step process. Furthermore, the present reaction is scalable up to one-gram scale. The commercially available palladium on carbon (5 wt%) was used as a heterogeneous catalyst and showed excellent recyclability (5 times) without significant loss in catalytic activity. Pleasingly, under our optimized conditions, the alpha alkyl substituted 2-iodoacetophenones exhibit good diastereoselectivity and predominantly (E)-2-vinylbenzoic acids were obtained with good to excellent yields.

An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization

Flow electrochemistry is an efficient methodology to generate radical intermediates. An electrochemical flow microreactor has been designed and manufactured to improve the efficiency of electrochemical flow reactions. With this device only little or no supporting electrolytes are needed, making processes less costly and enabling easier purification. This is demonstrated by the facile synthesis of amidyl radicals used in intramolecular hydroaminations to produce isoindolinones. The combination with inline mass spectrometry facilitates a much easier combination of chemical steps in a single flow process.

Stereospecific Formation of 2-benzoic Acids in an Unusual Reaction of Thiophthalides with Aldehydes

The reaction of thiophthalides 1 with aldehydes 3 in the presence of lithium tert-butoxide at -60 deg C to 25 deg C results in the stereospecific formation of only trans 2-(alk-1'-enyl)benzoic acids 4 in fairly good yields in one-pot operations.This react